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Article
Mechanistic inference of the metabolic rates underlying \(^{13}\) C breath test curves
Carbon stable isotope breath tests offer new opportunities to better understand gastrointestinal function in health and disease. However, it is often not clear how to isolate information about a gastrointestin...
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Article
Improving cost-effectiveness of endoscopic surveillance for Barrett’s esophagus by reducing low-value care: a review of economic evaluations
Individuals with Barrett’s esophagus are believed to be at 30–120× risk of develo** esophageal adenocarcinoma (EAC). Early detection and endoscopic treatment of dysplasia/early cancer confers a significant a...
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Article
Open AccessDevelopment of a non-invasive exhaled breath test for the diagnosis of head and neck cancer
Improving the ability to identify early-stage head and neck squamous cell carcinoma (HNSCC) can improve treatment outcomes and patient morbidity. We sought to determine the diagnostic accuracy of breath analys...
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Article
Open AccessBreath methane to hydrogen ratio as a surrogate marker of intestinal dysbiosis in head and neck cancer
Exhaled breath compounds can non-invasively detect head and neck squamous cell carcinoma (HNSCC). Here we investigated exhaled compounds related to intestinal bacterial carbohydrate fermentation. Fasting breat...
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Article
Open AccessDevelopment of a 13C Stable Isotope Assay for Dipeptidyl Peptidase-4 Enzyme Activity A New Breath Test for Dipeptidyl Peptidase Activity
Dipeptidyl peptidase-4 inhibitors (DPP4i) are a class of orally available, small molecule inhibitors for the management of Type-II diabetes. A rapid, real-time, functional breath test for DPP4 enzyme activity ...
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Article
Potential disease biomarkers: dipeptidyl peptidase 4 and fibroblast activation protein
The importance of the dipeptidyl peptidase 4 (DPP4) gene family in regulating critical biochemical pathways continues to emerge. The two most well-studied members of the family, DPP4 and fibroblast activation ...
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Article
Emerging evidence on the pathobiology of mucositis
Considerable progress has been made in our understanding of the biological basis for cancer therapy-induced mucosal barrier injury (mucositis). The last formal review of the subject by MASCC/ISOO was published...
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Article
Emerging evidence on the pathobiology of mucositis
Considerable progress has been made in our understanding of the biological basis for cancer therapy-induced mucosal barrier injury (mucositis). The last formal review of the subject by MASCC/ISOO was published...
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Article
Systematic review of agents for the management of gastrointestinal mucositis in cancer patients
The aim of this study was to review the available literature and define clinical practice guidelines for the use of agents for the prevention and treatment of gastrointestinal mucositis.
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Chapter and Conference Paper
Dipeptidyl Peptidases and Inflammatory Bowel Disease
