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  1. Article

    Open Access

    Range-wide and temporal genomic analyses reveal the consequences of near-extinction in Swedish moose

    Ungulate species have experienced severe declines over the past centuries through overharvesting and habitat loss. Even if many game species have recovered thanks to strict hunting regulation, the genome-wide ...

    Nicolas Dussex, Sara Kurland, Remi-André Olsen, Göran Spong in Communications Biology (2023)

  2. Article

    Open Access

    Sample identification and pedigree reconstruction in Wolverine (Gulo gulo) using SNP genoty** of non-invasive samples

    For conservation genetic studies using non-invasively collected samples, genome-wide data may be hard to acquire. Until now, such studies have instead mostly relied on analyses of traditional genetic markers s...

    Robert Ekblom, Malin Aronsson, Franziska Elsner-Gearing in Conservation Genetics Resources (2021)

  3. Article

    Open Access

    Review of the diet specialisation of the Blue-cheeked bee-eater (Merops persicus)

    Ecological specialisation, e.g. in terms of prey preferences, can have important implications for population biology. Bee-eaters are considered diet specialists; they hunt aerial insects, particularly hymenopt...

    Karl Gunnarsson, Robert Ekblom in Journal of Ornithology (2019)

  4. Article

    Open Access

    Development of transcriptome genetic markers for the great snipe (Gallinago media)

    We sequenced the transcriptomes of 14 great snipe (Gallinago media) males from the Gåvålia study population (central Norway) using Roche 454 technology. The assembled transcriptome sequences (RNA-Seq) was used to...

    Robert Ekblom, Biao Wang in Conservation Genetics Resources (2017)

  5. Article

    Open Access

    Patterns of sequencing coverage bias revealed by ultra-deep sequencing of vertebrate mitochondria

    Genome and transcriptome sequencing applications that rely on variation in sequence depth can be negatively affected if there are systematic biases in coverage. We have investigated patterns of local variation...

    Robert Ekblom, Linnéa Smeds, Hans Ellegren in BMC Genomics (2014)

  6. Article

    Open Access

    Whole genome sequencing of the black grouse (Tetrao tetrix): reference guided assembly suggests faster-Z and MHC evolution

    The different regions of a genome do not evolve at the same rate. For example, comparative genomic studies have suggested that the sex chromosomes and the regions harbouring the immune defence genes in the Maj...

    Biao Wang, Robert Ekblom, Ignas Bunikis, Heli Siitari, Jacob Höglund in BMC Genomics (2014)

  7. Article

    Open Access

    High-utility conserved avian microsatellite markers enable parentage and population studies across a wide range of species

    Microsatellites are widely used for many genetic studies. In contrast to single nucleotide polymorphism (SNP) and genoty**-by-sequencing methods, they are readily typed in samples of low DNA quality/concentr...

    Deborah A Dawson, Alexander D Ball, Lewis G Spurgin, David Martín-Gálvez in BMC Genomics (2013)

  8. Article

    Open Access

    Sequencing of the core MHC region of black grouse (Tetrao tetrix) and comparative genomics of the galliform MHC

    The MHC, which is regarded as the most polymorphic region in the genomes of jawed vertebrates, plays a central role in the immune system by encoding various proteins involved in the immune response. The chicke...

    Biao Wang, Robert Ekblom, Tanja M Strand, Silvia Portela-Bens in BMC Genomics (2012)

  9. No Access

    Article

    Genetic map** of the major histocompatibility complex in the zebra finch (Taeniopygia guttata)

    Genes of the major histocompatibility complex (MHC) have received much attention in immunology, genetics, and ecology because they are highly polymorphic and play important roles in parasite resistance and mat...

    Robert Ekblom, Jessica Stapley, Alex D. Ball, Tim Birkhead, Terry Burke in Immunogenetics (2011)

  10. No Access

    Article

    Balancing selection, sexual selection and geographic structure in MHC genes of Great Snipe

    Signatures of balancing selection are often found when investigating the extremely polymorphic regions of major histocompatibility complex (MHC) genes, and it is generally accepted that selective forces mainta...

    Robert Ekblom, Stein Are Sæther, Peder Fiske, John Atle Kålås, Jacob Höglund in Genetica (2010)

  11. Article

    Open Access

    Evolution of a cluster of innate immune genes (β-defensins) along the ancestral lines of chicken and zebra finch

    Avian β-defensins (AvBDs) represent a group of innate immune genes with broad antimicrobial activity. Within the chicken genome, previous work identified 14 AvBDs in a cluster on chromosome three. The release ...

    Olof Hellgren, Robert Ekblom in Immunome Research (2010)

  12. Article

    Open Access

    The genome of a songbird

    The genome of the zebra finch — a songbird and a model for the study of vertebrate brain, behaviour and evolution — has been sequenced. Its comparison with the chicken genome, the only other bird genome availa...

    Wesley C. Warren, David F. Clayton, Hans Ellegren, Arthur P. Arnold in Nature (2010)

  13. Article

    Open Access

    Digital gene expression analysis of the zebra finch genome

    In order to understand patterns of adaptation and molecular evolution it is important to quantify both variation in gene expression and nucleotide sequence divergence. Gene expression profiling in non-model or...

    Robert Ekblom, Christopher N Balakrishnan, Terry Burke, Jon Slate in BMC Genomics (2010)

  14. Article

    Open Access

    Gene duplication and fragmentation in the zebra finch major histocompatibility complex

    Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects. Avian MHC organization is of parti...

    Christopher N Balakrishnan, Robert Ekblom, Martin Völker, Helena Westerdahl in BMC Biology (2010)

  15. No Access

    Article

    Patterns of polymorphism in the MHC class II of a non-passerine bird, the great snipe (Gallinago media)

    The genomic organisation of the major histocompatibility complex (MHC) seems to vary considerably between different bird species. In order to understand this variation it is important to gather information fr...

    Robert Ekblom, Mats Grahn, Jacob Höglund in Immunogenetics (2003)