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Article
Cardiovascular health effects of wearing a particulate-filtering respirator to reduce particulate matter exposure: a randomized crossover trial
This randomized crossover trial sought to determine whether wearing a high-efficiency particulate-filtering respirator (PFR) improves cardiovascular function over 48 h among healthy college students in Tehran....
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Article
Open AccessEffects of isometric leg training on ambulatory blood pressure and morning blood pressure surge in young normotensive men and women
Despite the reported association between diurnal variations in ambulatory blood pressure (BP) and elevated cardiovascular disease risk, little is known regarding the effects of isometric resistance training (I...
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Article
Clearing the air to treat hypertension
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Article
Environmental determinants of cardiovascular disease: lessons learned from air pollution
Air pollution is well recognized as a major risk factor for chronic non-communicable diseases and has been estimated to contribute more to global morbidity and mortality than all other known environmental risk...
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Article
Coronary artery calcium scoring in patients with hypertension
Coronary artery calcium (CAC) is increased by high blood pressure (BP), predicts new-onset hypertension, and is a powerful predictor of atherosclerotic cardiovascular disease events in patients with and withou...
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Chapter
Approach to Secondary Hypertension
An imperfect, but widely-accepted distinction has been drawn between primary and secondary hypertension. As a description, “primary” is no more informative than the term it replaced, “essential.” Moreover, aut...
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Article
Open AccessStudy protocol for a stepped-wedge randomized cookstove intervention in rural Honduras: household air pollution and cardiometabolic health
Growing evidence links household air pollution exposure from biomass-burning cookstoves to cardiometabolic disease risk. Few randomized controlled interventions of cookstoves (biomass or otherwise) have quanti...
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Article
Reduction of personal PM2.5 exposure via indoor air filtration systems in Detroit: an intervention study
The adverse health effects of fine particulate matter (PM < 2.5 μm in diameter [PM2.5]) air pollution are well-documented. There is a growing body of evidence that high-efficiency particulate arrestance (HEPA) fi...
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Article
Echoes from Gaea, Poseidon, Hephaestus, and Prometheus: environmental risk factors for high blood pressure
High blood pressure (BP) affects over one billion people and is the leading risk factor for global mortality. While many lifestyle and genetic risk factors are well-accepted to increase BP, the role of the ext...
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Article
Isometric Handgrip as an Adjunct for Blood Pressure Control: a Primer for Clinicians
Considered a global health crisis by the World Health Organization, hypertension (HTN) is the leading risk factor for death and disability. The majority of treated patients do not attain evidence-based clinica...
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Article
Open AccessEffects of urban fine particulate matter and ozone on HDL functionality
Exposures to ambient particulate matter (PM) are associated with increased morbidity and mortality. PM2.5 (<2.5 μm) and ozone exposures have been shown to associate with carotid intima media thickness in humans. ...
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Article
GLP-1 Agonists and Blood Pressure: A Review of the Evidence
Type 2 diabetes mellitus (T2DM) is a major risk factor for cardiovascular disease. The presence of concomitant hypertension in diabetics is a major driver of excess cardiovascular risk. Glucagon-like peptide-1...
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Article
Understanding Air Pollution and Cardiovascular Diseases: Is It Preventable?
Fine particulate matter (<2.5 μm, PM2.5) air pollution is a leading risk factor for morbidity and mortality worldwide. The largest portion of adverse health effects is from cardiovascular diseases. In North Ameri...
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Article
Ambient Air Pollution: An Emerging Risk Factor for Diabetes Mellitus
Growing evidence supports that air pollution has become an important risk factor for develo** diabetes mellitus. Understanding the contributing effect of air pollution in population studies, elucidating the ...
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Article
The characteristics of coarse particulate matter air pollution associated with alterations in blood pressure and heart rate during controlled exposures
Although fine particulate matter (PM) air pollution <2.5 μm in aerodynamic diameter (PM2.5) is a leading cause of global morbidity and mortality, the potential health effects of coarse PM (2.5–10 μm in aerodynami...
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Article
Exploration of the composition and sources of urban fine particulate matter associated with same-day cardiovascular health effects in Dearborn, Michigan
The objective was to explore associations of chemical components and source factors of ambient fine particulate matter (aerodynamic diameter ≤2.5 μm; PM2.5) with cardiovascular (CV) changes following same-day exp...
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Article
Open AccessCentral IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes
Prior experimental and epidemiologic data support a link between exposure to fine ambient particulate matter (<2.5 μm in aerodynamic diameter, PM2.5) and development of insulin resistance/Type II diabetes mellitu...
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Article
Anxiety in the “Age of Hypertension”
In the USA, hypertension affects one in three adults, and anxiety disorders are the most commonly diagnosed mental health disorders. Both hypertension and anxiety have been studied extensively. Yet, a full und...
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Article
Cardiovascular impacts and micro-environmental exposure factors associated with continuous personal PM2.5 monitoring
The US Environmental Protection Agency’s (US EPA) Detroit Exposure and Aerosol Research Study (DEARS) has provided extensive data on human exposures to a wide variety of air pollutants and their impact on huma...
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Article
Open AccessAmbient fine particulate matter and ozone exposures induce inflammation in epicardial and perirenal adipose tissues in rats fed a high fructose diet
Inflammation and oxidative stress play critical roles in the pathogenesis of inhaled air pollutant-mediated metabolic disease. Inflammation in the adipose tissues niches are widely believed to exert important ...
