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    Article

    Coronary artery calcium scoring in patients with hypertension

    Coronary artery calcium (CAC) is increased by high blood pressure (BP), predicts new-onset hypertension, and is a powerful predictor of atherosclerotic cardiovascular disease events in patients with and withou...

    Richard L. Weinberg, Melvyn Rubenfire, Robert D. Brook in Journal of Human Hypertension (2020)

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    Chapter

    Secondary Prevention of Coronary Artery Disease

    The secondary prevention of coronary artery disease can be defined as a long-term management strategy for patients who have sustained an acute coronary syndrome or have chronic coronary heart disease. Goals of...

    Kavita Sharma, Claire Duvernoy, Melvyn Rubenfire in Practical Cardiology (2020)

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    Chapter

    Primary Prevention of Coronary Artery Disease

    The advances in the detection and management of cardiovascular diseases (CVDs) have resulted in a 31% decline in the death rates attributable to CVD in the United States from 2001 to 2011 [1]. Coronary, or isc...

    Kavita Sharma, Melvyn Rubenfire, Eric R. Bates in Practical Cardiology (2020)

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    Chapter

    Pulmonary Embolism

    Pulmonary embolism (PE) and deep venous thrombosis (DVT) are two manifestations of one disease, venous thromboembolism (VTE). DVT is confirmed by venography in more than 80% of patient with PE that is proven b...

    John G. Weg, Melvyn Rubenfire, Gbemiga Sofowora in Practical Cardiology (2020)

  5. Article

    Open Access

    Diagnosis of acquired generalized lipodystrophy in a single patient with T-cell lymphoma and no exposure to Metreleptin

    Metreleptin, a recombinant methionyl -human -leptin, was approved to treat patients with generalized lipodystrophy (GL) in February 2014. However, leptin therapy has been associated with the development of lym...

    Nazanene H. Esfandiari, Melvyn Rubenfire in Clinical Diabetes and Endocrinology (2019)

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    Article

    Doxorubicin-induced cardiac dysfunction in unselected patients with a history of early-stage breast cancer

    Cardiomyopathy is a known complication of anthracycline-based adjuvant chemotherapy and is more commonly reported in population-based studies of breast cancer survivors than in clinical trials. This study pro...

    Megan E. V. Caram, Cui Guo, Monika Leja in Breast Cancer Research and Treatment (2015)

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    Article

    HDL Cholesterol and Cardiovascular Outcomes: What Is the Evidence?

    The relationship between low concentrations of high density lipoprotein cholesterol (HDL-C) and heightened risk for cardiovascular (CV) disease has been known for decades. Despite the consistent inverse relati...

    Melvyn Rubenfire, Robert D. Brook in Current Cardiology Reports (2013)

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    Article

    Diagnostic value of resting tricuspid regurgitation velocity and right ventricular ejection flow parameters for the detection of exercise induced pulmonary arterial hypertension

    Our objectives were to evaluate resting tricuspid regurgitation velocity (TRV) and right ventricular outflow tract velocity curve (RVOTvc) profiles as markers for development of exercise induced pulmonary arteria...

    Eduardo Bossone, Erick Avelar, David S. Bach in The International Journal of Cardiac Imagi… (2000)

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    Chapter

    Natural History of Experimental Myocardial Ischemia. Observations in Acute and Chronic Studies

    Introduction of ST segment map** to experimental (Maroko et al., 1971) and clinical investigations (Awan et al., 1976; Madias et al., 1975 and 1976) on the effects of interventions intended to reduce ischemi...

    Waldemar J. Wajszczuk M.D. in Models and Measurements of the Cardiac Ele… (1982)

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    Chapter

    Epicardial St-Segment Map** in Acute Myocardial Ischemia. Examples of Coincidental Experimental Interventions which may Affect Interpretation

    The technique of multi-electrode epicardial recording of electrical activity of the heart is now commonly used for evaluation of the ischemic injury in experimental studies (Maroko et al., 1971). Its ability t...

    Waldemar J. Wajsczuk M.D., Jacek Przybylski in Models and Measurements of the Cardiac Ele… (1982)