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  1. No Access

    Reference Work Entry In depth

    Glyco-engineered Therapeutic Antibodies as a Second-Generation Antibody Therapy

    Since the establishment of monoclonal antibody production using mouse hybridoma technology in the 1980s, there has been expanding progress and continuous technological improvement in the development of therape...

    Rinpei Niwa, Kenya Shitara, Mitsuo Satoh in Glycoscience: Biology and Medicine (2015)

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    Chapter and Conference Paper

    Non-fucosylated Therapeutic Antibodies: The Next Generation of Therapeutic Antibodies

    Therapeutic antibody IgG1 has two N-linked oligosaccharide chains bound to the Fc region. The oligosaccharides are of the complex biantennary type, composed of a trimannosyl core structure with the presence or ab...

    Mitsuo Satoh, Shigeru Iida… in Animal Cell Technology: Basic & Applied As… (2009)

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    Article

    Non-fucosylated therapeutic antibodies: the next generation of therapeutic antibodies

    Therapeutic antibody IgG1 has two N-linked oligosaccharide chains bound to the Fc region. The oligosaccharides are of the complex biantennary type, composed of a trimannosyl core structure with the presence or...

    Katsuhiro Mori, Shigeru Iida, Naoko Yamane-Ohnuki, Yutaka Kanda… in Cytotechnology (2007)