10 Result(s)
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Article
Open AccessExpression of unfolded protein response genes in post-transplantation liver biopsies
Cholestatic liver diseases are a major source of morbidity and mortality that can progress to end-stage liver disease and hyperbilirubinemia is a hallmark of cholestasis. There are few effective medical therap...
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Article
Open AccessA dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas
In order to achieve higher dosages than previously used in clinical trials, we conducted a phase I trial to determine the maximum tolerated dose (MTD) for the combination of erlotinib and sirolimus for the tre...
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Article
Open AccessRosette-forming glioneuronal tumor: a pineal region case with IDH1 and IDH2 mutation analyses and literature review of 43 cases
Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a mixed glio-neuronal neoplasm recently codified by the World Health Organization WHO Classification of Central Nervous System (CNS) Tumors (20...
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Article
Open AccessPancreatic adenocarcinoma in type 2 progressive familial intrahepatic cholestasis
BSEP disease results from mutations in ABCB11, which encodes the bile salt export pump (BSEP). BSEP disease is associated with an increased risk of hepatobiliary cancer.
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Open AccessBile composition in Alagille Syndrome and PFIC patients having Partial External Biliary Diversion
Partial External Biliary Diversion (PEBD) is a surgical intervention to treat children with Progressive Familial Intrahepatic Cholestasis (PFIC) and Alagille syndrome (AGS). PEBD can reduce disease progression...
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Article
Optimal Operative Strategies in Repair of Juxtarenal Abdominal Aortic Aneurysms
In an effort to identify preoperative and perioperative factors impacting outcome in repair of juxtarenal abdominal aortic aneurysm (JRAAA), hospital records and CT scans (for calcification, intraluminal throm...
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Article
EEG Changes during Awake Carotid Endarterectomy
To determine the reason for differing shunt rates based on electroencephalographic (EEG) and neurologic changes during general and regional anesthetic, respectively, we compared simultaneous EEG tracings and n...
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Article
Clinical Implications of Internal Iliac Artery Embolization in Endovascular Repair of Aortoiliac Aneurysms
To overcome constraints imposed by iliac artery anatomy, the anatomic inclusion criteria for endovascular aortic aneurysm repair can be extended by means of intentional coil occlusion of one or both internal i...
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Article
External Beam Irradiation for Inhibition of Intimal Hyperplasia following Prosthetic Bypass: Preliminary Results
To determine whether external beam irradiation delivered immediately after graft implantation can inhibit anastomotic intimal hyperplasia (IH) 1 month following polytetrafluoroethylene (PTFE) bypass in a sheep...
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Article
Alcohol Withdrawal after Open Aortic Surgery
