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Article
QTL map** for flowering time in a maize-teosinte population under well-watered and water-stressed conditions
Maize grain yield can be greatly reduced when flowering time coincides with drought conditions, which delays silking and consequently increases the anthesis-silking interval. Although the genetic basis of dela...
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Article
Open AccessPopulation genomics of Zea species identifies selection signatures during maize domestication and adaptation
Maize (Zea mays L. ssp. mays) was domesticated from teosinte (Zea mays ssp. parviglumis) about 9000 years ago in southwestern Mexico and adapted to a range of environments worldwide. Researchers have depicted the...
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Chapter
Data Pre-Processing and Modeling Factors
This chapter covers several important pre-processing steps. Before implementing a demand prediction method, it is crucial to process the raw data in order to extract as much predictive power as possible from t...
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Chapter
Tree-Based Methods
This chapter explores tree-based methods for demand prediction. These methods are widely used given their strong predictive power. We consider three types of methods: Decision Tree, Random Forest, and Gradient...
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Chapter
Evaluation and Visualization
In this chapter, we summarize all the results obtained so far and compare the different methods in terms of prediction accuracy. We then present several simple ways to visualize and communicate the prediction ...
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Chapter
Conclusion and Advanced Topics
This chapter aims to conclude this book by first summarizing all the concepts and methods we covered. We then briefly discuss seven more advanced topics related to demand prediction, such as deep learning meth...
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Chapter
Introduction
This chapter introduces the topic of demand prediction for retail applications. We first present several managerial motivations behind demand prediction and discuss the potential practical impact of having goo...
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Chapter
Clustering Techniques
This chapter discusses how to leverage clustering techniques in the context of demand prediction for retail applications. Specifically, our goal is to aggregate the data across different SKUs to improve the pr...
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Chapter
More Advanced Methods
In this chapter, we discuss two more advanced methods, which are recent advancements in demand prediction. We first present the Prophet method, which is an open-sourced library released by Facebook researchers...
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Chapter
Common Demand Prediction Methods
This chapter covers several common methods for demand prediction. We start by presenting the basic linear regression method applied to one SKU. We then explain how to properly structure the dataset. We next di...
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Article
Open AccessChimeric antigen receptor T cell targeting EGFRvIII for metastatic lung cancer therapy
Lung cancer is the most common incident cancer and the leading cause of cancer death. In recent years, the development of tumor immunotherapy especially chimeric antigen receptor T (CAR-T) cell has shown a pro...
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Article
Open AccessAdoptive cell transfer therapy for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. This malignancy is associated with poor prognosis and high mortality. Novel approaches for prolonging the overall survival of patient...
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Article
Patterns of genomic variation in Chinese maize inbred lines and implications for genetic improvement
Genetic relationships among Chinese maize germplasms reveal historical trends in heterotic patterns from Chinese breeding programs and identify line Dan340 as a potential genome donor for elite inbred line Zhe...
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Article
Acylation of Exenatide by Glycolic Acid and its Anti-Diabetic Activities in db/db Mice
To prepare acylated exenatide analogues and investigate their biological properties for guiding the development of PLGA formulations of exenatide.
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Article
Enhancement of bioavailability by formulating rhEPO ionic complex with lysine into PEG–PLA micelle
A composite micelle of ionic complex encapsulated into poly(ethylene glycol)-poly(d,l-lactide) (PEG–PLA) di-block copolymeric micelles was used for protein drug delivery to improve its pharmacokinetic performance...
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Article
EEG Changes during Awake Carotid Endarterectomy
To determine the reason for differing shunt rates based on electroencephalographic (EEG) and neurologic changes during general and regional anesthetic, respectively, we compared simultaneous EEG tracings and n...
