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Article
Open AccessFactors associated with recurrence and survival length following relapse in patients with neuroblastoma
Despite therapeutic advances, survival following relapse for neuroblastoma patients remains poor. We investigated clinical and biological factors associated with length of progression-free and overall survival...
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Article
Open AccessSpace-time clustering of childhood central nervous system tumours in Yorkshire, UK
We specifically tested the aetiological hypothesis that a factor influencing geographical or temporal heterogeneity of childhood central nervous system (CNS) tumour incidence was related to exposure to a trans...
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Article
Open AccessThe epidemiology of bone cancer in 0 - 39 year olds in northern England, 1981 - 2002
There is a paucity of recent epidemiological data on bone cancers. The aim of this study was to describe incidence and survival patterns for bone cancers diagnosed during 1981 - 2002.
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Article
Open AccessSpace-time clustering analyses of type 1 diabetes in children from north-east England: support for an infectious aetiology?
The aetiology of type 1 diabetes in children is uncertain. A number of recent studies have suggested an infectious aetiology. It has been postulated that an infectious agent may be involved. Support for this h...
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Article
Open AccessSex-specific incidence and temporal trends in solid tumours in young people from Northern England, 1968–2005
This study examined sex-specific patterns and temporal trends in the incidence of solid tumours in the Northern Region of England from 1968 to 2005. This updates earlier analyses from the region where sex was ...
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Article
Relative frequency and morphology of cancers in carriers of germline TP53 mutations
The spectrum and frequency of cancers associated with germline TP53 mutations are uncertain. To address this issue a cohort of individuals from 28 families with Li-Fraumeni syndrome, segregating germline TP53 ...
