4 Result(s)
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Rianne van Binsbergen
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Article
Open AccessGenomic prediction using imputed whole-genome sequence data in Holstein Friesian cattle
In contrast to currently used single nucleotide polymorphism (SNP) panels, the use of whole-genome sequence data is expected to enable the direct estimation of the effects of causal mutations on a given trait....
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Article
Open AccessThe effect of rare alleles on estimated genomic relationships from whole genome sequence data
Relationships between individuals and inbreeding coefficients are commonly used for breeding decisions, but may be affected by the type of data used for their estimation. The proportion of variants with low Mi...
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Article
Whole-genome sequencing of 234 bulls facilitates map** of monogenic and complex traits in cattle
Ben Hayes and colleagues report the whole-genome sequencing of 234 bulls as phase one of the 1000 bull genomes project. They identify 28.3 million variants in the cattle sequences and also report genome-wide a...
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Article
Open AccessAccuracy of imputation to whole-genome sequence data in Holstein Friesian cattle
The use of whole-genome sequence data can lead to higher accuracy in genome-wide association studies and genomic predictions. However, to benefit from whole-genome sequence data, a large dataset of sequenced i...
