12 Result(s)
within
Reinhard Brunkhorst
-
Article
Open AccessThe TRANSNephro-study examining a new transition model for post-kidney transplant adolescents and an analysis of the present health care: study protocol for a randomized controlled trial
The transition from pediatric to nephrology care is not yet a standardized procedure. The result is an increased risk of deteriorating transplant function, with the potential for premature transplant failure.
-
Chapter
Hypokalemia
Hypokalemia is defined as a serum potassium of <3.5 mmol/l. It can be graded in mild (potassium 3–3.5 mmol/l, whole body deficit 130–300 mmol/l), moderate (potassium 2.5–3.0 mmol/l, whole body deficit 300–500 ...
-
Chapter
Hyperkalemia
Normal serum potassium levels are between 3.5 and 5.0 mmol/l; hyperkalemia refers to serum potassium >5.5 mmol/l. About 98 % of the body’s potassium is found inside cells, with the remainder in the extracellul...
-
Chapter
Nephrotic Syndrome
Nephrotic syndrome is a complex of symptoms including proteinuria (>3.5 g/24 h), edema, hypoalbuminemia, and hypercholesterinemia. It is characterized by a damage of the capillary walls of the glomeruli, which...
-
Chapter
Uremia
Uremia is defined as a number of clinical symptoms observed in stages 4 and 5 (GFR 15–29 and <15 ml/min resp.) of chronic kidney disease (CKD). These symptoms may vary in order and severity. Without improvemen...
-
Article
A population-based study comparing biosimilar versus originator erythropoiesis-stimulating agent consumption in 6,117 patients with renal anaemia
There are concerns that biosimilar erythropoiesis-stimulating agents (ESAs) are less effective than the originator ESAs. The objective of our study was to investigate differences between originator and biosimi...
-
Article
Epidemiology of sepsis in Germany: results from a national prospective multicenter study
To determine the prevalence and mortality of ICU patients with severe sepsis in Germany, with consideration of hospital size.
-
Article
Attitude of patients toward transplantation of xenogeneic organs
Background: The prospect of xenotransplantation has stimulated considerable hopes as well as major concerns. The question of whether or not patients accept xenografts is influenced not only by scientific facts b...
-
Article
Pronounced renal vasoconstriction and systemic hypertension in renal transplant patients treated with cyclosporin A versus FK 506
This prospective study investigated hypertension and renal vasoconstriction develo** during the 1st year after renal transplantation in patients randomly allocated to treatment with FK 506 (n = 28) or CyA (n =...
-
Article
High mortality from urothelial carcinoma despite regular tumor screening in patients with analgesic nephropathy after renal transplantation
Patients with end-stage renal failure due to analgesic nephropathy have an increased risk of develo** a urothelial carcinoma. To determine the impact of renal transplantation on the frequency of urothelial c...
-
Chapter
Malignancies in transplant patients under cyclosporine treatment for more than 10 years
Long-term immunosuppressive therapy after renal transplantation with different kinds of drugs carries an increased risk of development of malignant disease [1–4]. Except for preexisting or undetected cases mos...
-
Chapter
Micropuncture Studies on Mechanisms of Proteinuria in Early Adriamycin-Nephrosis in MWF-RATS
The sensitivity of the kidney to many compounds is well recognized, and sequences of pathological events have been documented in detail. A model compound to induce nephrotic syndrome in rodents is adriamycin, ...
