12 Result(s)
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Reinder Vos de Wael
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Article
Open AccessTau follows principal axes of functional and structural brain organization in Alzheimer’s disease
Alzheimer’s disease (AD) is a brain network disorder where pathological proteins accumulate through networks and drive cognitive decline. Yet, the role of network connectivity in facilitating this accumulation...
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Open AccessVariation in spatial dependencies across the cortical mantle discriminates the functional behaviour of primary and association cortex
Recent theories of cortical organisation suggest features of function emerge from the spatial arrangement of brain regions. For example, association cortex is located furthest from systems involved in action a...
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Open AccessAssortative mixing in micro-architecturally annotated brain connectomes
The wiring of the brain connects micro-architecturally diverse neuronal populations, but the conventional graph model, which encodes macroscale brain connectivity as a network of nodes and edges, abstracts awa...
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Open AccessAn Open MRI Dataset For Multiscale Neuroscience
Multimodal neuroimaging grants a powerful window into the structure and function of the human brain at multiple scales. Recent methodological and conceptual advances have enabled investigations of the interpla...
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Open AccessGenetic and phylogenetic uncoupling of structure and function in human transmodal cortex
Brain structure scaffolds intrinsic function, supporting cognition and ultimately behavioral flexibility. However, it remains unclear how a static, genetically controlled architecture supports flexible cogniti...
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Open AccessA tale of two gradients: differences between the left and right hemispheres predict semantic cognition
Decomposition of whole-brain functional connectivity patterns reveals a principal gradient that captures the separation of sensorimotor cortex from heteromodal regions in the default mode network (DMN). Functi...
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Open AccessConnectivity alterations in autism reflect functional idiosyncrasy
Autism spectrum disorder (ASD) is commonly understood as an alteration of brain networks, yet case-control analyses against typically-develo** controls (TD) have yielded inconsistent results. Here, we devise...
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The ENIGMA Toolbox: multiscale neural contextualization of multisite neuroimaging datasets
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Open AccessMacroscale and microcircuit dissociation of focal and generalized human epilepsies
Thalamo-cortical pathology plays key roles in both generalized and focal epilepsies, but there is little work directly comparing these syndromes at the level of whole-brain mechanisms. Using multimodal imaging...
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Open AccessBrainSpace: a toolbox for the analysis of macroscale gradients in neuroimaging and connectomics datasets
Understanding how cognitive functions emerge from brain structure depends on quantifying how discrete regions are integrated within the broader cortical landscape. Recent work established that macroscale brain...
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Open AccessA molecular gradient along the longitudinal axis of the human hippocampus informs large-scale behavioral systems
The functional organization of the hippocampus is distributed as a gradient along its longitudinal axis that explains its differential interaction with diverse brain systems. We show that the location of human...
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Open AccessAtypical functional connectome hierarchy in autism
One paradox of autism is the co-occurrence of deficits in sensory and higher-order socio-cognitive processing. Here, we examined whether these phenotypical patterns may relate to an overarching system-level im...
