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  1. Article

    Open Access

    Plasma metabolites and physical function in patients undergoing hemodialysis

    Impaired physical function contributes to falls, fractures, and mortality among patients undergoing dialysis. Using a metabolomic approach, we identified metabolite alterations and effect size-based composite ...

    Ranjani N. Moorthi, Sharon M. Moe, Thomas O’Connell in Scientific Reports (2024)

  2. No Access

    Article

    Skeletal Muscle Complications in Chronic Kidney Disease

    To provide an overview of the recent literature investigating the pathophysiology of skeletal muscle changes, interventions for skeletal muscle, and effects of exercise in chronic kidney disease (CKD).

    Ashley D. Troutman, Eliott Arroyo, Kenneth Lim in Current Osteoporosis Reports (2022)

  3. Article

    Open Access

    Skeletal muscle metabolic responses to physical activity are muscle type specific in a rat model of chronic kidney disease

    Chronic kidney disease (CKD) leads to musculoskeletal impairments that are impacted by muscle metabolism. We tested the hypothesis that 10-weeks of voluntary wheel running can improve skeletal muscle mitochond...

    Keith G. Avin, Meghan C. Hughes, Neal X. Chen, Shruthi Srinivasan in Scientific Reports (2021)

  4. Article

    Open Access

    Sarcopenia, frailty and cachexia patients detected in a multisystem electronic health record database

    Sarcopenia, cachexia and frailty have overlap** features and clinical consequences, but often go unrecognized. The objective was to detect patients described by clinicians as having sarcopenia, cachexia or f...

    Ranjani N. Moorthi, Ziyue Liu, Sarah A. El-Azab in BMC Musculoskeletal Disorders (2020)

  5. No Access

    Article

    Effects of Excessive Dietary Phosphorus Intake on Bone Health

    The purpose of this review is to provide an overview of dietary phosphorus, its sources, recommended intakes, and its absorption and metabolism in health and in chronic kidney disease and to discuss recent fin...

    Colby J. Vorland, Elizabeth R. Stremke, Ranjani N. Moorthi in Current Osteoporosis Reports (2017)

  6. Article

    Erratum to: Diet and Diabetic Kidney Disease: Plant Versus Animal Protein

    Ranjani N. Moorthi, Colby J. Vorland, Kathleen M. Hill Gallant in Current Diabetes Reports (2017)

  7. No Access

    Article

    Diet and Diabetic Kidney Disease: Plant Versus Animal Protein

    The goal of this review is to present an overview of the evidence on the effectiveness of plant-based diets in delaying progression of diabetic kidney disease (DKD).

    Ranjani N. Moorthi, Colby J. Vorland, Kathleen M. Hill Gallant in Current Diabetes Reports (2017)

  8. No Access

    Article

    Bone is Not Alone: the Effects of Skeletal Muscle Dysfunction in Chronic Kidney Disease

    Chronic kidney disease (CKD) is associated with a decline in muscle mass, strength, and function, collectively called “sarcopenia.” Sarcopenia is associated with hospitalizations and mortality in CKD and is th...

    Keith G. Avin, Ranjani N. Moorthi in Current Osteoporosis Reports (2015)