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Article
Open AccessThe influence of surgical technique guidance and surgeon’s experience on the femoral head assembly in total hip arthroplasty
The importance of the assembly procedure on the taper connection strength is evident. However, existent surgical technique guides frequently lack comprehensive and precise instructions in this regard. The aim ...
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Article
Open AccessIL-6-induced response of human osteoblasts from patients with rheumatoid arthritis after inhibition of the signaling pathway
Interleukin (IL-) 6 is a critical factor in inflammatory processes of rheumatoid arthritis (RA). This is of high interest as the progression of RA may lead to the implantation of joint endoprostheses, which is...
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Article
Open AccessEstablishing safe high hydrostatic pressure devitalization thresholds for autologous head and neck cancer vaccination and reconstruction
High hydrostatic pressure specifically devitalizes cells and tissues without major changes in their molecular structure. Hence, high hydrostatic pressure may enhance the development of whole-cell anti-tumor va...
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Article
Open AccessThe effect of a digital-assisted group rehabilitation on clinical and functional outcomes after total hip and knee arthroplasty—a prospective randomized controlled pilot study
The rising number of total hip and knee arthroplasties and the decreasing availability of physiotherapists require clinically and economically effective rehabilitation approaches. Therefore, the present pilot ...
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Article
Open AccessBarefoot walking is more stable in the gait of balance recovery in older adults
Perturbation-based balance training on a treadmill is an emerging method of gait stability training with a characteristic task nature that has had positive and sustained effects on balance recovery strategies ...
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Article
Open AccessLower extremity joint compensatory effects during the first recovery step following slip** and stumbling perturbations in young and older subjects
The lower extremity may play a crucial role in compensating for gait perturbations. The study aimed to explore the mechanism of perturbation compensation by investigating the gait characteristics and lower ext...
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Article
Open AccessNovel integrated workflow allows production and in-depth quality assessment of multifactorial reprogrammed skeletal muscle cells from human stem cells
Skeletal muscle tissue engineering aims at generating biological substitutes that restore, maintain or improve normal muscle function; however, the quality of cells produced by current protocols remains insuff...
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Article
Open AccessKinematics and kinetics comparison of ultra-congruent versus medial-pivot designs for total knee arthroplasty by multibody analysis
Nowadays, several configurations of total knee arthroplasty (TKA) implants are commercially available whose designs resulted from clinical and biomechanical considerations. Previous research activities led to ...
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Article
Open AccessMonitoring the maturation of the sarcomere network: a super-resolution microscopy-based approach
The in vitro generation of human cardiomyocytes derived from induced pluripotent stem cells (iPSC) is of great importance for cardiac disease modeling, drug-testing applications and for regenerative medicine. ...
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Chapter and Conference Paper
An Artificial Potential Field Algorithm for Path Planning of Redundant Manipulators Based on Navigation Functions
In this work, we propose a novel artificial potential field off-line path planning algorithm for robot manipulators. The potential field is defined using navigation functions, and the parameters of the navigat...
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Article
Open AccessThe future of basic science in orthopaedics and traumatology: Cassandra or Prometheus?
Orthopaedic and trauma research is a gateway to better health and mobility, reflecting the ever-increasing and complex burden of musculoskeletal diseases and injuries in Germany, Europe and worldwide. Basic sc...
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Article
Open AccessFinite element analysis of bone remodelling with piezoelectric effects using an open-source framework
Bone tissue exhibits piezoelectric properties and thus is capable of transforming mechanical stress into electrical potential. Piezoelectricity has been shown to play a vital role in bone adaptation and remode...
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Living Reference Work Entry In depth
Verhalten unterschiedlicher Implantatwerkstoffe unter mechanischer Belastung
In der Orthopädischen Chirurgie kommen unterschiedliche Implantatmaterialien aus den Werkstoffgruppen der Metalle, Keramiken und Polymere, die sich hinsichtlich ihrer mechanischen und biologischen Eigenschafte...
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Article
Open AccessThe role of antibiotic-loaded bone cement in complicated knee arthroplasty: relevance of gentamicin allergy and benefit from revision surgery — a case control follow-up study and algorithmic approach
Antibiotic-loaded (particularly gentamicin) bone cement (BC) is widely used in total joint arthroplasty (TJA) to prevent periprosthetic infections (PPIs), but may itself cause implant failure. In light of a co...
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Chapter and Conference Paper
A Detailed Kinematic Multibody Model of the Shoulder Complex After Total Shoulder Replacement
Multibody modeling allows reproducible and comparative analyses of ...
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Article
Open AccessNeuro-musculoskeletal flexible multibody simulation yields a framework for efficient bone failure risk assessment
Fragility fractures are a major socioeconomic problem. A non-invasive, computationally-efficient method for the identification of fracture risk scenarios under the representation of neuro-musculoskeletal dynam...
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Article
Open AccessDuration of antibiotic treatment and risk of recurrence after surgical management of orthopaedic device infections: a multicenter case-control study
Device-related infections in orthopaedic and trauma surgery are a devastating complication with substantial impact on morbidity and mortality. Systemic suppressive antibiotic treatment is regarded an integral ...
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Article
Open AccessImpact of compression stockings on leg swelling after arthroscopy – a prospective randomised pilot study
Post-operative limb swelling may negatively affect the outcome of arthroscopic surgery and prolong rehabilitation. The aim of this pilot study was to evaluate the effect of compression stockings versus no comp...
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Article
Primary stability of total hip stems: does surgical technique matter?
With this preliminary study we hypothesized a modified implantation technique may lead to higher primary stability than the conventional one.
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Article
Open AccessHigh wear resistance of femoral components coated with titanium nitride: a retrieval analysis
The objective of this study was to evaluate the in vivo wear resistance of cobalt-chromium femoral components coated with titanium nitride (TiN). Our null hypothesis was that the surface damage and the thickn...
