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  1. Article

    Open Access

    Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: a multicentre randomized clinical pilot trial

    Fever improves pathogen control at a significant metabolic cost. No randomized clinical trials (RCT) have compared fever treatment thresholds in critically ill children. We performed a pilot RCT to determine w...

    Mark J. Peters, Kerry Woolfall, Imran Khan, Elisabeth Deja in Critical Care (2019)

  2. Article

    Open Access

    Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS)

    Sepsis is one of the main reasons for non-elective admission to pediatric intensive care units (PICUs), but little is known about determinants influencing outcome. We characterized children admitted with commu...

    Navin P. Boeddha, Luregn J. Schlapbach, Gertjan J. Driessen in Critical Care (2018)

  3. No Access

    Article

    Attitudes towards fever amongst UK paediatric intensive care staff

    The role played by fever in the outcome of critical illness in children is unclear. This survey of medical and nursing staff in 35 paediatric intensive care units and transport teams in the United Kingdom and ...

    Thomas Brick, Rachel S. Agbeko, Patrick Davies in European Journal of Pediatrics (2017)

  4. Article

    Mind over matter? Pain, withdrawal and sedation in paediatric critical care

    Rachel S. Agbeko, Andrew Argent, Graeme MacLaren in Intensive Care Medicine (2016)

  5. Article

    Visualizing secondary brain insults: does the emperor have new clothes?

    Karim Asehnoune, J. Claude Hemphill III, Rachel S. Agbeko in Intensive Care Medicine (2015)

  6. Article

    Tools for revealing uncomfortable truths? Measuring child-centred health-related quality of life after paediatric intensive care

    Rachel S. Agbeko, Jeffrey P. Burns, Mark J. Peters in Intensive Care Medicine (2015)

  7. Article

    Open Access

    Optimism and no longer foolishness? Haematology/oncology and the PICU

    Mark J. Peters, Rachel S. Agbeko in Intensive Care Medicine (2014)

  8. Article

    Genetic polymorphisms in the endotoxin receptor may influence platelet count as part of the acute phase response in critically ill children

    To determine if common polymorphisms in the endotoxin recognition complex influence the acute phase response as determined by the development of the systemic inflammatory response syndrome (SIRS) and platelet ...

    Rachel S. Agbeko, John W. Holloway, Meredith L. Allen, Shu Ye in Intensive Care Medicine (2010)

  9. No Access

    Article

    Angiotensin-converting enzyme D allele does not influence susceptibility to acute hypoxic respiratory failure in children

    The D allele of the I/D polymorphism in the angiotensin-converting enzyme (ACE) gene has been associated with an increased risk of ARDS in critically ill adults and severity of bronchopulmonary dysplasia in pre-t...

    Adrian Plunkett, Rachel S. Agbeko, KaWah Li, Steve E. Humphries in Intensive Care Medicine (2008)

  10. No Access

    Article

    Mannose-binding lectin and pulmonary morbidity in premature infants

    Rachel S. Agbeko, Mark J. Peters in Intensive Care Medicine (2008)