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Article
Spontaneous Rhythms in Physiological Control Systems
MEAN arterial blood pressure in man undergoes spontaneous and broadly repetitive fluctuations with a typical period of about 10 s. We present an explanation for these fluctuations which we believe may also be ...
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Article
Biological Control
Principles of Biological Regulation: An Introduction to Feedback Systems.
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Article
The analysis and simulation of the human thermoregulatory control system
The paper describes a study into one aspect of the thermoregulatory control system in man. An analysis of this control system led to the hypothesis that thermoregulation in humans is achieved by two basic cont...
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Article
Measurement of heart-rate variability: Part 1—Comparative study of heart-rate variability analysis methods
A definition of heart-rate variability (h.r.v.) is given. The use of h.r.v. measurement in both clinical applications and the neural cardiovascular research is discussed. For the latter applications, four diff...
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Article
Measurement of heart-rate variability: Part 2-hardware digital device for the assessment of heart-rate variability
Part 1 of the paper was dedicated to some general aspects of h.r.v. measurements. In Part 2, the spectral properties of the integral pulse frequency modulator (i.p.f.m.) are shown. The choice of a hardware dev...
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Article
Matching techniques for clinical models of the circulation
Several models of the circulation have been developed in physiological research. Such models can be matched to patient measurements and then used as a clinical diagnostic tool. We have examined methods for mat...
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Article
Mode analysis of physiological oscillators intercoupled via pure time delays
The study of bi-directionally coupled oscillators is relevant in biological modelling of such systems as gastro-intestinal electrical activity, cardiac pacemarkers, cardiovascular and respiratory interactions ...
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Chapter
Modelling Respiratory Sinus Arrhythmia and its Application to the Study of Neuropathy
Evidence for respiratory waves in blood pressure was first presented by Ludwig in 1847. More recently these fluctuations have become known as Mayer waves (Penaz, 1978); the wave of respiratory origin is now ca...
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Article
Raster-scan method for observing physiological entrainment phenomena
A simple raster-scan display, using a small interactive microcomputer with graphics capability, is described and gives visual indication of various entrainment-type phenomena. In particular, almostentrainment ...
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Article
Calibration of entrainment raster scans
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Article
Comparison of computer models of the human arterial system for the assessment of clinical data
Arterial pressure and flow measurements can be analysed using a mathematical model of the circulation. A comparison of four models of the circulation used in this way is presented. The results indicate some cr...
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Chapter
Heart Rate Variability in Autonomic Neuropaths and Newborn Babies
This Chapter will discuss two areas where the application of HRV analysis is likely to be of clinical significance. First the application to HRV is neuropaths and second to HRV in the newborn. In both case the...
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Chapter
Heart Rate Variability in Normal Adults
With the development of Cybernetics, Weiner (1948) showed that there was considerable potential in the application to the study of biological systems of techniques of analysis normally employed in the physical...
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Chapter
3-D Visualization of Arterial Structures and Flow Phenomena
In this chapter we describe the reconstruction of arterial structures using three-dimensional solid modelling. The alternative approaches to three dimensional modelling are discussed and the voxel space system...
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Article
Biomedical signal processing (in four parts)
This is the first of a series of four tutorial papers on biomedical signal processing. It provides an introduction to terminology and basic ideas for testing for randomness and trend, and for the determination...
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Chapter and Conference Paper
Development of an Integrated Diagnostic Workstation for the Display and Analysis of Multi-Modal Medical Images
Due to the increasing availability of high quality digital images from a range of imaging modalities and the emergence of networked imaging suites, there exists significant value for a facility which will faci...
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Chapter and Conference Paper
Digital Image Processing of X-Ray and MR Breast Images
Breast disease, both malignant and benigh affects a large percentage of women. An X-ray mammogram is the standard examination for symptomatic women and now, via screening programmes, for asymptomatic women. Th...
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Chapter and Conference Paper
Information in Magnetic Resonance Images: The Parameterisation of Signal, Contrast and Noise
Performance assessment of medical imaging systems should play a key role in the management of the system throughout its life-cycle from system selection and purchase, through acceptance testing to routine qual...
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Article
Biomedical signal processing (in four parts)
This is the second in a series of four tutorial papers on biomedical signal processing, and it concerns the relationships between commonly used frequency transforms. It begins with the Fourier series and Fouri...
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Article
Biomedical signal processing (in four parts)
This is the third in a series of four tutorial papers on biomedical signal processing and concerns the estimation of the power spectrum (PS) and coherence function (CF) od biomedical data. The PS is introduced...
