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Chapter and Conference Paper
Information Driven Care Pathways and Procedures
The paper addresses the issue of the implementation of care pathways in electronic form. Within the National Health Service (NHS) of England, Care Pathways are becoming increasingly important. These are typica...
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Chapter and Conference Paper
Modeling biological systems in Laplace Domain for Synthetic Biology Design
Synthetic Biology is becoming increasing importance in the field of medicine. Synthetic biology involves the use of engineering approach to design and construct biological systems using standard interconnected...
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Article
Transient phase locking patterns among respiration, heart rate and blood pressure during cardiorespiratory synchronisation in humans
The interactions between respiration, heart rate and blood pressure variability (HRV, BPV), are considered to be of paramount importance for the study of the functional organisation of the autonomic nervous sy...
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Article
Object-based three-dimensional X-ray imaging
A form of three-dimensional X-ray imaging, called Object 3-D, is introduced, where the relevant subject material is represented as discrete ‘objects’. The surface of each such object is derived accurately from...
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Article
Biomedical signal processing (in four parts)
This is the third in a series of four tutorial papers on biomedical signal processing and concerns the estimation of the power spectrum (PS) and coherence function (CF) od biomedical data. The PS is introduced...
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Chapter and Conference Paper
Development of an Integrated Diagnostic Workstation for the Display and Analysis of Multi-Modal Medical Images
Due to the increasing availability of high quality digital images from a range of imaging modalities and the emergence of networked imaging suites, there exists significant value for a facility which will faci...
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Chapter and Conference Paper
Digital Image Processing of X-Ray and MR Breast Images
Breast disease, both malignant and benigh affects a large percentage of women. An X-ray mammogram is the standard examination for symptomatic women and now, via screening programmes, for asymptomatic women. Th...
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Chapter and Conference Paper
Information in Magnetic Resonance Images: The Parameterisation of Signal, Contrast and Noise
Performance assessment of medical imaging systems should play a key role in the management of the system throughout its life-cycle from system selection and purchase, through acceptance testing to routine qual...
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Article
Biomedical signal processing (in four parts)
This is the second in a series of four tutorial papers on biomedical signal processing, and it concerns the relationships between commonly used frequency transforms. It begins with the Fourier series and Fouri...
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Article
Biomedical signal processing (in four parts)
This is the first of a series of four tutorial papers on biomedical signal processing. It provides an introduction to terminology and basic ideas for testing for randomness and trend, and for the determination...
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Chapter
3-D Visualization of Arterial Structures and Flow Phenomena
In this chapter we describe the reconstruction of arterial structures using three-dimensional solid modelling. The alternative approaches to three dimensional modelling are discussed and the voxel space system...
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Chapter
Heart Rate Variability in Autonomic Neuropaths and Newborn Babies
This Chapter will discuss two areas where the application of HRV analysis is likely to be of clinical significance. First the application to HRV is neuropaths and second to HRV in the newborn. In both case the...
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Chapter
Heart Rate Variability in Normal Adults
With the development of Cybernetics, Weiner (1948) showed that there was considerable potential in the application to the study of biological systems of techniques of analysis normally employed in the physical...
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Article
Comparison of computer models of the human arterial system for the assessment of clinical data
Arterial pressure and flow measurements can be analysed using a mathematical model of the circulation. A comparison of four models of the circulation used in this way is presented. The results indicate some cr...
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Article
Calibration of entrainment raster scans
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Article
Raster-scan method for observing physiological entrainment phenomena
A simple raster-scan display, using a small interactive microcomputer with graphics capability, is described and gives visual indication of various entrainment-type phenomena. In particular, almostentrainment ...
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Article
Mode analysis of physiological oscillators intercoupled via pure time delays
The study of bi-directionally coupled oscillators is relevant in biological modelling of such systems as gastro-intestinal electrical activity, cardiac pacemarkers, cardiovascular and respiratory interactions ...
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Chapter
Modelling Respiratory Sinus Arrhythmia and its Application to the Study of Neuropathy
Evidence for respiratory waves in blood pressure was first presented by Ludwig in 1847. More recently these fluctuations have become known as Mayer waves (Penaz, 1978); the wave of respiratory origin is now ca...
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Article
Matching techniques for clinical models of the circulation
Several models of the circulation have been developed in physiological research. Such models can be matched to patient measurements and then used as a clinical diagnostic tool. We have examined methods for mat...
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Article
Measurement of heart-rate variability: Part 2-hardware digital device for the assessment of heart-rate variability
Part 1 of the paper was dedicated to some general aspects of h.r.v. measurements. In Part 2, the spectral properties of the integral pulse frequency modulator (i.p.f.m.) are shown. The choice of a hardware dev...