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Article
Open Access‘Everything was just getting worse and worse’: deteriorating job quality as a driver of doctor emigration from Ireland
Medicine is a high-status, high-skill occupation which has traditionally provided access to good quality jobs and relatively high salaries. In Ireland, historic underfunding combined with austerity-related cut...
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Article
Open AccessPrevalence of myeloma precursor state monoclonal gammopathy of undetermined significance in 12372 individuals 10–49 years old: a population-based study from the National Health and Nutrition Examination Survey
We studied the prevalence of monoclonal gammopathy of undetermined significance (MGUS) in younger individuals, age 10–49 years, using samples from the National Health and Nutritional Examination Survey (NHANES...
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Article
ALDH1A3 is epigenetically regulated during melanocyte transformation and is a target for melanoma treatment
Despite the promising targeted and immune-based interventions in melanoma treatment, long-lasting responses are limited. Melanoma cells present an aberrant redox state that leads to the production of toxic ald...
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Article
Natural killer cells in acute myeloid leukemia patients: from phenotype to transcriptomic analysis
Chemotherapies allow complete remission in more than 50 % of patients with acute myeloid leukemia (AML), however, with frequent relapse. This suggests that residual leukemic cells may escape to chemotherapy an...
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Article
Serum immunoglobulin free light chains and post-transplant lymphoproliferative disorder among allogeneic hematopoietic stem cell transplant recipients
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Article
Sepsis and neutropenia in hematological malignancies
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Article
Racial disparities in the prevalence of monoclonal gammopathies: a population-based study of 12 482 persons from the National Health and Nutritional Examination Survey
Multiple myeloma (MM) incidence is markedly higher in blacks compared with whites, which may be related to a higher prevalence of monoclonal gammopathy of undetermined significance (MGUS). Our objective was to...
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Article
Effetti metabolici della liotironina nell’ipotiroidismo: studio randomizzato, in doppio-cieco, crossover di liotironina versus levotiroxina
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Article
Rasmussen’s Aneurysm: A Forgotten Entity?
We present the case of a rare entity which is a complication of a disease process that had almost disappeared from the Western World. With the recent resurgence in reported cases of Mycobacterium tuberculosis (TB...
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Article
Book review
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Chapter and Conference Paper
Feasibility of High Dose Melphalan (140 mg/m2) and Peripheral Blood Stem Cell Support as Consolidation for Patients over 60 Years with Acute Myeloid Leukemia in First Complete Remission
The optimal post remission treatment of acute myeloid leukemia(AML) in patients over 60years remains controversial and is regularly disappointing This is explained by a higher incidence of adverse prognostic f...
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Article
Role of high-dose therapy and initial response in survival of poor-risk patients with aggressive non-Hodgkin's lymphoma: a retrospective series on 126 patients from a single center
It is now established that a subgroup of non-Hodgkin's lymphoma (NHL) patients probably benefit from high-dose therapy (HDT). We therefore retrospectively analyzed survival of 126 consecutive patients with lar...
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Chapter and Conference Paper
Intensive Sequential Chemotherapy for Untreated Poor-Risk Non-Hodgkin’s Lymphoma
First generation chemotherapy regimens like CHOP as well as second and third generation regimens — using multiple non-cross-resistant drugs and alternating cycles — have limited efficacy in high-risk non-Hodgk...
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Article
Detection of CBFβ/MYH11 fusion transcripts in acute myeloid leukemia: heterogeneity of cytological and molecular characteristics
Pericentric inversion of chromosome 16, translocation (16;16) and del(16q), resulting in a chimerical fusion of CBFβ and MYH11 genes, are typically seen in the M4Eo French–American–British (FAB) classification...
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Article
Irish Thoracic Society
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Article
Irish thoracic society
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Article
Royal academy of medicine in Ireland section of medicine
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Article
Irish thoracic society
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Article
Multifactorial hypokalaemia in a beer drinker
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Article
Irish thoracic society