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  1. Article

    Open Access

    The BDNF Val66Met polymorphism regulates glucocorticoid-induced corticohippocampal remodeling and behavioral despair

    The BDNF Val66Met polymorphism has been associated with sensitivity to stress and affective disorders. We therefore sought to model the inter-causality of these relationships under controlled laboratory condit...

    M Notaras, X Du, J Gogos, M van den Buuse, R A Hill in Translational Psychiatry (2017)

  2. No Access

    Article

    The Potential of Gonadal Hormone Signalling Pathways as Therapeutics for Dementia

    Dementia is an ever-expanding problem facing an ageing society. Currently, there is a sharp paucity of treatment strategies. It has long been known that sex hormones, namely 17β-estradiol and testosterone, pos...

    X. Du, R. A. Hill in Journal of Molecular Neuroscience (2016)

  3. Article

    Open Access

    Analyzing the influence of BDNF heterozygosity on spatial memory response to 17β-estradiol

    The recent use of estrogen-based therapies as adjunctive treatments for the cognitive impairments of schizophrenia has produced promising results; however the mechanism behind estrogen-based cognitive enhancem...

    Y W C Wu, X Du, M van den Buuse, R A Hill in Translational Psychiatry (2015)

  4. No Access

    Article

    Change in Nox4 expression is accompanied by changes in myogenic marker expression in differentiating C2C12 myoblasts

    Myoblast differentiation is mediated by a cascade of changes in gene expression including transcription factors such as myogenin. Subsequent to myoblast differentiation, there is an increase in expression of t...

    S. Acharya, A. M. Peters, A. S. Norton in Pflügers Archiv - European Journal of Phys… (2013)