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  1. Article

    Open Access

    The BDNF Val66Met polymorphism regulates glucocorticoid-induced corticohippocampal remodeling and behavioral despair

    The BDNF Val66Met polymorphism has been associated with sensitivity to stress and affective disorders. We therefore sought to model the inter-causality of these relationships under controlled laboratory condit...

    M Notaras, X Du, J Gogos, M van den Buuse, R A Hill in Translational Psychiatry (2017)

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  2. Article

    Open Access

    BDNF Val66Met genotype determines hippocampus-dependent behavior via sensitivity to glucocorticoid signaling

    M Notaras, R Hill, J A Gogos, M van den Buuse in Molecular Psychiatry (2016)

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  3. Article

    Open Access

    Dissociating the therapeutic effects of environmental enrichment and exercise in a mouse model of anxiety with cognitive impairment

    Clinical evidence indicates that serotonin-1A receptor (5-HT1AR) gene polymorphisms are associated with anxiety disorders and deficits in cognition. In animal models, exercise (Ex) and environmental enrichment (E...

    J Rogers, U Vo, LS Buret, TY Pang, H Meiklejohn… in Translational Psychiatry (2016)

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  4. No Access

    Article

    The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy

    Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development, differentiation and plasticity in both the develo** and adult brain. A single-nucleotide polymorphism in the proregion of ...

    M Notaras, R Hill, M van den Buuse in Molecular Psychiatry (2015)

  5. Article

    Open Access

    Analyzing the influence of BDNF heterozygosity on spatial memory response to 17β-estradiol

    The recent use of estrogen-based therapies as adjunctive treatments for the cognitive impairments of schizophrenia has produced promising results; however the mechanism behind estrogen-based cognitive enhancem...

    Y W C Wu, X Du, M van den Buuse, R A Hill in Translational Psychiatry (2015)

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  6. Article

    Open Access

    Locomotor hyperactivity in 14-3-3ζ KO mice is associated with dopamine transporter dysfunction

    Dopamine (DA) neurotransmission requires a complex series of enzymatic reactions that are tightly linked to catecholamine exocytosis and receptor interactions on pre- and postsynaptic neurons. Regulation of do...

    H Ramshaw, X Xu, E J Jaehne, P McCarthy, Z Greenberg, E Saleh… in Translational Psychiatry (2013)

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  7. No Access

    Article

    Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3ζ deficiency

    Complex neuropsychiatric disorders are believed to arise from multiple synergistic deficiencies within connected biological networks controlling neuronal migration, axonal pathfinding and synapse formation. He...

    P-S Cheah, H S Ramshaw, P Q Thomas, K Toyo-oka, X Xu, S Martin… in Molecular Psychiatry (2012)

  8. No Access

    Article

    Phospholipase C-β1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration

    Phospholipase C-β1 (PLC-β1) is a rate-limiting enzyme implicated in postnatal-cortical development and neuronal plasticity. PLC-β1 transduces intracellular signals from specific muscarinic, glutamate and serotoni...

    C E McOmish, E Burrows, M Howard, E Scarr, D Kim, H-S Shin, B Dean… in Molecular Psychiatry (2008)

  9. No Access

    Article

    Enhanced effect of dopaminergic stimulation on prepulse inhibition in mice deficient in the alpha subunit of Gz

    Gz is a member of the Gi G protein family associated with dopamine D2-like receptors; however, its functions remain relatively unknown. The aim of the present study was to investigate prepulse inhibition (PPI) of...

    M. van den Buuse, S. Martin, J. Brosda, K. J. Leck, K. I. Matthaei… in Psychopharmacology (2005)

  10. No Access

    Article

    Does metoclopramide increase sympathetic drive to the heart?

    Dr. B. Kingwell, M. van den Buuse in Clinical Autonomic Research (2003)

  11. No Access

    Article

    Abstracts of papers pharmacological meeting

    H. W. G. M. Boddeke, T. J. W. Jap, J. G. Hugtenburg… in Pharmaceutisch Weekblad (1987)

  12. No Access

    Article

    Abstracts of papers

    M. W. E. Teunissen, W. Bakker, P. Willemsen, D. D. Breimer… in Pharmaceutisch Weekblad (1982)