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    Article

    A fast and efficient HLA multimer-based sorting procedure that induces little apoptosis to isolate clinical grade human tumor specific T lymphocytes

    HLA multimers are now widely used to stain and sort CD8 T lymphocytes specific for epitopes from viral or tumoral antigens presented in an HLA class I context. However, the transfer of this technology to a cli...

    Régis Bouquié, Annabelle Bonnin, Karine Bernardeau… in Cancer Immunology, Immunotherapy (2009)

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    Article

    PBMC are as good a source of tumor-reactive T lymphocytes as TIL after selection by Melan-A/A2 multimer immunomagnetic sorting

    Choosing a reliable source of tumor-specific T lymphocytes and an efficient method to isolate these cells still remains a critical issue in adoptive cellular therapy (ACT). In this study, we assessed the capac...

    Nathalie Labarrière, Nadine Gervois, Annabelle Bonnin… in Cancer Immunology, Immunotherapy (2008)