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  1. Article

    Open Access

    Cost-utility analysis of curative and maintenance repetitive transcranial magnetic stimulation (rTMS) for treatment-resistant unipolar depression: a randomized controlled trial protocol

    Depression is a debilitating and costly disease for our society, especially in the case of treatment-resistant depression (TRD). Repetitive transcranial magnetic stimulation (rTMS) is an effective adjuvant the...

    Samuel Bulteau, Andrew Laurin, Christelle Volteau, Cécile Dert, Lydie Lagalice… in Trials (2020)

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    Article

    A fast and efficient HLA multimer-based sorting procedure that induces little apoptosis to isolate clinical grade human tumor specific T lymphocytes

    HLA multimers are now widely used to stain and sort CD8 T lymphocytes specific for epitopes from viral or tumoral antigens presented in an HLA class I context. However, the transfer of this technology to a cli...

    Régis Bouquié, Annabelle Bonnin, Karine Bernardeau… in Cancer Immunology, Immunotherapy (2009)

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    Article

    A new tyrosinase epitope recognized in the HLA-B*4002 context by CTL from melanoma patients

    Melanoma reactive CTL were obtained by stimulating PBL from a melanoma patient in remission since 1994 following adjuvant TIL immunotherapy, with the autologous melanoma cell line. They were cloned by limiting...

    Yann Godet, Annabelle Bonnin, Yannik Guilloux… in Cancer Immunology, Immunotherapy (2009)

  4. No Access

    Article

    PBMC are as good a source of tumor-reactive T lymphocytes as TIL after selection by Melan-A/A2 multimer immunomagnetic sorting

    Choosing a reliable source of tumor-specific T lymphocytes and an efficient method to isolate these cells still remains a critical issue in adoptive cellular therapy (ACT). In this study, we assessed the capac...

    Nathalie Labarrière, Nadine Gervois, Annabelle Bonnin… in Cancer Immunology, Immunotherapy (2008)

  5. No Access

    Article

    Infusion of Melan-A/Mart-1 specific tumor-infiltrating lymphocytes enhanced relapse-free survival of melanoma patients

    Adoptive therapy of cancer has been mostly tested in advanced cancer patients using tumor-infiltrating lymphocytes (TIL). Following discouraging results likely due to poor tumor-specificity of TIL and/or high ...

    Houssem Benlalam, Virginie Vignard, Amir Khammari… in Cancer Immunology, Immunotherapy (2007)