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Article
Open AccessCharacteristics of vaginal microbiota in various cervical intraepithelial neoplasia: a cross-sectional study
Precancerous lesions of cervical cancer exhibit characteristics indicative of natural progression. To prevent overtreatment of patients whose cervical intraepithelial neoplasia (CIN) in regression and to predi...
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Article
Open AccessSmall RNA sequencing provides insights into molecular mechanism of flower development in Rhododendron pulchrum Sweet
Rhododendron pulchrum sweet, a member of the Ericaceae family possessing valuable horticultural properties, is widely distributed in the temperate regions. Though serving as bioindicator of metal pollution, the m...
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Article
Open AccessThe impact of COVID-19 lockdown on the quality of life of Chinese football referees: the chain mediating role of occupational stress and job burnout
COVID-19 lockdown measures have had a great negative impact on the development of sports competition in China, as well as on the quality of life of football referees. This study aims to explore the impact of l...
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Article
Epigenetic inhibition of lncRNA GMDS-AS1 by methyltransferase ESET promoted cell viability and metastasis of hepatocellular carcinoma
Long noncoding RNA (lncRNAs) GMDS-AS1 has been reported as a tumor regulator in tumor growth and metastasis, but its effect in hepatocellular carcinoma (HCC) remains unclear. ESET, a histone H3K9 methyl-transf...
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Article
Complete chloroplast genome sequence and phylogenetic analysis of Rhododendron molle G. Don, an endangered Ericaceae species located on Dabie Mountains (central China)
Rhododendron molle G. Don, an endemic species of the Ericaceae family, possesses valuable medicinal and horticultural values. In this research, R. molle cp genome proved to be a typical quadripartite structure wi...
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Article
Open AccessCoronary artery disease in a patient with Addison’s disease: a case report and literature review
Addison’s disease which is due to dysfunction of the adrenal gland, with abnormal secretion of glucocorticoids and mineralocorticoids, is rare. By inducing inflammation and disorders of water and electrolyte m...
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Implicit and Explicit Evaluations of Chinese Targeted Poverty Alleviation Policy: Experimental Evidence from Attitudes of the Rural Poor in Western China
True attitudes of individuals toward anti-poverty policies are not easily observed in policy evaluation. The Chinese targeted poverty alleviation policy (TPAP), an anti-poverty policy, has attracted more atten...
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Article
Open AccessEarly assessment of ventricular synchronization and function after left bundle-branch-area pacing with right bundle-branch block
To evaluate ventricular synchronization and function in patients with right bundle-branch block after left bundle-branch-area pacing (LBBAP) by echocardiography.
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Article
Open AccessHuman monocytes differentiate into tumor-associated macrophages upon SKOV3 cells coculture and/or lysophosphatidic acid stimulation
Serous ovarian carcinoma is the most common type of ovarian carcinoma. Tumor-associated macrophages (TAMs) promote ovarian cancer progression. Most macrophages are generated by monocyte differentiation. Lysoph...
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Article
Situational factors shape moral judgements in the trolley dilemma in Eastern, Southern and Western countries in a culturally diverse sample
The study of moral judgements often centres on moral dilemmas in which options consistent with deontological perspectives (that is, emphasizing rules, individual rights and duties) are in conflict with options...
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Publisher Correction: Situational factors shape moral judgements in the trolley dilemma in Eastern, Southern and Western countries in a culturally diverse sample
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Article
Open AccessClinical analysis and artificial intelligence survival prediction of serous ovarian cancer based on preoperative circulating leukocytes
Circulating leukocytes are an important part of the immune system. The aim of this work is to explore the role of preoperative circulating leukocytes in serous ovarian carcinoma and investigate whether they ca...
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Article
Open AccessFOXA1 can be modulated by HDAC3 in the progression of epithelial ovarian carcinoma
FOXA1 is associated with malignant tumors, but the function of FOXA1 in EOC is unclear. HDAC3 can influence the proliferation, migration and invasion ability of EOC. In this study, we wanted to explore the fun...
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Development of high quality EST-SSR markers in Rhododendron obtusum Hort. ex Wats. and their use in determining relationships among Rhododendron cultivars
Rhododendron, large vascular plant genera with tens of thousands of cultivars, possesses valuable horticultural, medicinal, and ecological properties. However, the genetic studies have been hindered due to lack o...
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Article
Transcriptome analysis of flower color variation in five Rhododendron species (Ericaceae)
Rhododendron genus is famous with important ecology impacts, ornamental values, and high medicine values. To obtain a comprehensive overview of anthocyanin regulatory networks, RNA-seq and de novo assembly of fiv...
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Article
Evaluating Left Ventricular Systolic Synchronicity with Real-Time 3D Echocardiography in Newborns
Knowing the normal values of left ventricular (LV) systolic synchronicity in the early neonatal period is very important for understanding myocardial function. This retrospective study analyzed data of 105 new...
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Article
Open AccessA 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
New therapies are urgently needed for Alzheimer’s disease (AD). Sodium oligomannate (GV-971) is a marine-derived oligosaccharide with a novel proposed mechanism of action. The first phase 3 clinical trial of G...
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Article
Open AccessAccuracy of HPV E6/E7 mRNA examination using in situ hybridization in diagnosing cervical intraepithelial lesions
The consistency of pathologists in the diagnosis of cervical intraepithelial neoplasia (CINs) is not ideal, especially between low- and high-grade squamous intraepithelial lesions (LSIL and HSIL). This study w...
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Metabolite profiling of violet, white and pink flowers revealing flavonoids composition patterns in Rhododendron pulchrum Sweet
Flower color is the major characteristics and critical breeding program for most Rhododendron species. However, little is known about their coloration mechanism and color inheritance. In this study, petal pigment...
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Article
Correction to: Dynamic Changes of Antibodies to SARS-CoV-2 in COVID-19 Patients at Early Stage of Outbreak
Due to type-setting error, the affiliation of author Huaqing Shu and Shuzhen Wang was mislabeled.
