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Article
Open AccessImpact of Different Promoters on Episomal Vectors Harbouring Characteristic Motifs of Matrix Attachment Regions
We previously demonstrated that the characteristic sequence of matrix attachment regions (MARs) allows transgenes to be maintained episomally in CHO cells. In the present study, six commonly used promoters fro...
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Article
Open AccessTreating Colon Cancer Cells with FK228 Reveals a Link between Histone Lysine Acetylation and Extensive Changes in the Cellular Proteome
The therapeutic value of FK228 as a cancer treatment option is well known and various types of cancer have been shown to respond to this drug. However, the complete mechanism of FK228 and the affect it has on ...
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Article
The effect of recombinant lentiviral vector encoding miR-145 on human esophageal cancer cells
miR-145, a newly identified microRNA molecule, is hypothesized to function as a tumor suppressor, but this activity has not been investigated in esophageal l carcinoma (EC). The aim of this study was to invest...