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  1. Article

    Open Access

    Exploring immune related gene signatures and mechanisms linking non alcoholic fatty liver disease to atrial fibrillation through transcriptome data analysis

    Atrial fibrillation (AF) and related cardiovascular complications pose a heavy burden to patients and society. Mounting evidence suggests a close association between nonalcoholic fatty liver disease (NAFLD) an...

    Keke Wu, Jiayi Zhu, Yingxu Ma, Yong Zhou, Qiuzhen Lin, Tao Tu in Scientific Reports (2023)

  2. Article

    Open Access

    Ceftazidime-assisted synthesis of ultrasmall chitosan nanoparticles for biofilm penetration and eradication of Pseudomonas aeruginosa

    Pseudomonas aeruginosa (P. aeruginosa) infections present a grave threat to immunocompromised individuals, particularly those with cystic fibrosis due to the development of bacterial biofilms. In this study, we e...

    **aoran Zheng, Min Gao, Liangquan Wu, **n Lu, Qiuqi Lin, Hai Zhong in Scientific Reports (2023)

  3. Article

    Open Access

    Integrated single-cell and bulk RNA sequencing analysis identifies a prognostic signature related to ferroptosis dependence in colorectal cancer

    Ferroptosis is an iron-dependent form of cell death induced by lipid oxidation with an essential role in diseases, including cancer. Since prognostic value of ferroptosis-dependent related genes (FDRGs) in col...

    **aochen Xu, **nwen Zhang, Qiumei Lin, Yuling Qin, Yihao Liu in Scientific Reports (2023)

  4. Article

    Open Access

    IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella

    Metastasis accounts for 90% of cancer-related deaths and, currently, there are no effective clinical therapies to block the metastatic cascade. A need to develop novel therapies specifically targeting fundamen...

    Qiubin Lin, Li Rong, **an Jia, Renhao Li, Bin Yu, **gchu Hu in Nature Communications (2021)

  5. Article

    Open Access

    COVID-Net: a tailored deep convolutional neural network design for detection of COVID-19 cases from chest X-ray images

    The Coronavirus Disease 2019 (COVID-19) pandemic continues to have a devastating effect on the health and well-being of the global population. A critical step in the fight against COVID-19 is effective screeni...

    Linda Wang, Zhong Qiu Lin, Alexander Wong in Scientific Reports (2020)

  6. Article

    Open Access

    Clinical significance of miR-1180-3p in hepatocellular carcinoma: a study based on bioinformatics analysis and RT-qPCR validation

    miRNAs play an indispensable role in human carcinogenesis. Dysregulated miR-1180-3p has been observed in several types of cancer, including hepatocellular carcinoma (HCC). This study intends to correlate the e...

    Zihan Zhou, **anguo Zhou, Yanji Jiang, Moqin Qiu, in Scientific Reports (2020)

  7. Article

    Open Access

    Female bias in an immigratory population of Cnaphalocrocis medinalis moths based on field surveys and laboratory tests

    Sex ratio bias is common in migratory animals and can affect population structure and reproductive strategies, thereby altering population development. However, little is known about the underlying mechanisms ...

    Jia-Wen Guo, Fan Yang, ** Li, **ang-Dong Liu, Qiu-Lin Wu, Gao Hu in Scientific Reports (2019)

  8. Article

    Open Access

    Correlation between Jejunal Microbial Diversity and Muscle Fatty Acids Deposition in Broilers Reared at Different Ambient Temperatures

    Temperature, which is an important environmental factor in broiler farming, can significantly influence the deposition of fatty acids in muscle. 300 one-day-old broiler chicks were randomly divided into three ...

    **ng Li, Zhenhui Cao, Yuting Yang, Liang Chen, Jian** Liu in Scientific Reports (2019)

  9. Article

    Open Access

    A strongly adhesive hemostatic hydrogel for the repair of arterial and heart bleeds

    Uncontrollable bleeding is a major problem in surgical procedures and after major trauma. Existing hemostatic agents poorly control hemorrhaging from traumatic arterial and cardiac wounds because of their weak...

    Yi Hong, Feifei Zhou, Yujie Hua, **anzhu Zhang, Chengyao Ni in Nature Communications (2019)

  10. Article

    Open Access

    Free radical sensors based on inner-cutting graphene field-effect transistors

    Due to ultra-high reactivity, direct determination of free radicals, especially hydroxyl radical (•OH) with ultra-short lifetime, by field-effect transistor (FET) sensors remains a challenge, which hampers eva...

    Zhen Wang, Kongyang Yi, Qiuyuan Lin, Lei Yang, **aosong Chen in Nature Communications (2019)

  11. Article

    Open Access

    Baduan** exercise intervention for community adults at risk of ischamic stroke: A randomized controlled trial

    The aim of current study was to assess the effects of Baduan** exercise on cerebrovascular function, cardiac structure and cardiac function, static pulmonary function, traditional risk factors of CVD and the ...

    Guohua Zheng, Bai Chen, Qianying Fang, Qiu Lin, **g Tao, Lidian Chen in Scientific Reports (2019)

  12. Article

    Author Correction: A series of energetic metal pentazolate hydrates

    In this Letter, under Methods section ‘[Na(H2O)(N5)]⋅2H2O (2)’, the description “the intermediate product arylpentazole (5.000 g, 26.18 mmol)” should have read “the intermediate product sodium salt of arylpentazo...

    Yuangang Xu, Qian Wang, Cheng Shen, Qiuhan Lin, Pengcheng Wang, Ming Lu in Nature (2018)

  13. Article

    Open Access

    Techniques and long-term effects of transjugular intrahepatic portosystemic shunt on liver cirrhosis-related thrombotic total occlusion of main portal vein

    Portal vein hypertension (PVH) in liver cirrhosis complicated with portal venous thrombosis (PVT) has been mainly treated with transjugular intrahepatic portosystemic shunt (TIPS). The clinical effects of TIPS...

    Lei Wang, Fuliang He, Zhendong Yue, Hongwei Zhao, Zhenhua Fan in Scientific Reports (2017)

  14. No Access

    Article

    A series of energetic metal pentazolate hydrates

    Metal complexes of the pentazole anion exhibit multiple coordination modes, through ionic, covalent and hydrogen-bonding interactions, and good thermal stability with onset decomposition temperatures greater t...

    Yuangang Xu, Qian Wang, Cheng Shen, Qiuhan Lin, Pengcheng Wang, Ming Lu in Nature (2017)

  15. Article

    Open Access

    Noninvasive Imaging of Ras Activity by Monomolecular Biosensor Based on Split-Luciferase Complementary Assay

    Deregulated activity of Ras GTPases has been observed in many types of human cancers, and contributes to the diverse aspects of carcinogenesis. Although the significance in tumorigenesis has been widely accept...

    Liang Chen, Wei Bing Leng, De Zhi Li, Hong Wei **a, Min Ren in Scientific Reports (2017)

  16. Article

    Open Access

    Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma

    3β-Hydroxysteroid-Δ24 reductase (DHCR24), the final enzyme of the cholesterol biosynthetic pathway, has been associated with urogenital neoplasms. However, the function of DHCR24 in endometrial cancer (EC) rem...

    Miao Dai, **ao-Lu Zhu, Fei Liu, Qin-Yang Xu, Qiu-Lin Ge in Scientific Reports (2017)

  17. Article

    Open Access

    Metabolic effects of basic fibroblast growth factor in streptozotocin-induced diabetic rats: A 1H NMR-based metabolomics investigation

    The fibroblast growth factors (FGFs) family shows a great potential in the treatment of diabetes, but little attention is paid to basic FGF (bFGF). In this study, to explore the metabolic effects of bFGF on di...

    **aodong Lin, Liangcai Zhao, Shengli Tang, Qi Zhou, Qiuting Lin in Scientific Reports (2016)

  18. Article

    Open Access

    Mucoepidermoid carcinoma arising in Warthin’s tumor of the parotid gland: Clinicopathological characteristics and immunophenotypes

    Mucoepidermoid carcinoma (MEC), an extremely rare tumor, arises from the epithelial component of preexisting parotid Warthin tumors (WT). Among the 309 cases of surgically resected WTs in Chinese PLA General H...

    Chunkai Yu, Zhigang Song, Zhibo **ao, Qiushi Lin, **aoqun Dong in Scientific Reports (2016)

  19. Article

    Open Access

    CD4+CD25+ T Cells in primary malignant hypertension related kidney injury

    CD4+CD25+ T cells are critical for maintenance of immunologic self-tolerance. We measured the number of CD4+CD25+ cells in the patients with primary malignant hypertension related kidney injury, to explore the mo...

    Hongdong Huang, Yang Luo, Yumei Liang, **dai Long, Youming Peng in Scientific Reports (2016)

  20. Article

    Open Access

    In Vitro Assessment Reveals Parameters-Dependent Modulation on Excitability and Functional Connectivity of Cerebellar Slice by Repetitive Transcranial Magnetic Stimulation

    Repetitive transcranial magnetic stimulation (rTMS) is an increasingly common technique used to selectively modify neural excitability and plasticity. There is still controversy concerning the cortical respons...

    Rongyu Tang, Guanghao Zhang, **echuan Weng, Yao Han, Yiran Lang in Scientific Reports (2016)

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