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Article
Association between type 1 diabetes and systemic lupus erythematosus: a Mendelian randomization study
Observational studies have shown that there is a bidirectional relationship between type 1 diabetes (T1D) and systemic lupus erythematosus (SLE); the causality of this association remains elusive and may be af...
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Article
Open AccessMaresin1 ameliorates MSU crystal-induced inflammation by upregulating Prdx5 expression
Maresin1 (MaR1) is a potent lipid mediator that exhibits significant anti-inflammatory activity in the context of several inflammatory diseases. A previous study reported that MaR1 could suppress MSU crystal-i...
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Article
Citric acid cross-linked regenerated bacterial cellulose as biodegradable film for food packaging
The global depletion of petrochemical resources, along with the environmental problems caused by the widespread use of traditional plastics, has brought more attention to exploring biodegradable materials. How...
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Article
Purinergic P2X7R as a potential target for pancreatic cancer
Pancreatic cancer is one of the deadliest types of cancer, with a death rate nearly equal to the incidence. The P2X7 receptor (P2X7R) is a kind of extracellular adenosine triphosphate (ATP)-gated ion channel w...
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Article
Open AccessRAD-seq as an effective strategy for heterogenous variety identification in plants—a case study in Italian Ryegrass (Lolium multiflorum)
The primary approach for variety distinction in Italian ryegrass is currently the DUS (distinctness, uniformity and stability) test based on phenotypic traits. Considering the diverse genetic background within...
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Article
Open AccessTaurocholic acid inhibits the response to interferon-α therapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8+ T and NK cell function
Pegylated interferon-alpha (PegIFNα) therapy has limited effectiveness in hepatitis B e-antigen (HBeAg)-positive chronic hepatitis B (CHB) patients. However, the mechanism underlying this failure is poorly und...
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Article
Open AccessGenomic survey sequencing, development and characterization of single- and multi-locus genomic SSR markers of Elymus sibiricus L
Siberian wildrye (Elymus sibiricus L.) attracts considerable interest for grassland establishment and pasture recovery in the Qinghai-Tibet Plateau (QTP) due to its excellence in strong stress tolerance, high nut...
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Article
Open AccessiMarmot: an integrative platform for comparative and functional genomics of marmots
Marmots are large Holarctic rodents with unique biological features, making them potential animal models in various research fields. Due to the rapid accumulation of the genetic data in marmots, a highly integ...
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Article
Open AccessMechanisms of lung toxicity induced by biomass burning aerosols
Carbonaceous aerosols emitted from indoor and outdoor biomass burning are major risk factors contributing to the global burden of disease. Wood tar aerosols, namely, tar ball particles, compose a substantial f...
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Article
Glutathione S-transferase M1 null genotype is associated with increased risk of oral cancer in East Asians: a meta-analysis
The association between glutathione S-transferase M1 (GSTM1) null genotype and risk of oral cancer in East Asians is uncertain owing to the inconclusive results from published studies. In the present study, we...
