-
Article
Open AccessTripartite motif containing 26 prevents steatohepatitis progression by suppressing C/EBPδ signalling activation
Currently potential preclinical drugs for the treatment of nonalcoholic steatohepatitis (NASH) and NASH-related pathopoiesis have failed to achieve expected therapeutic efficacy due to the complexity of the pa...
-
Article
Open AccessHepatocyte phosphatase DUSP22 mitigates NASH-HCC progression by targeting FAK
Nonalcoholic steatohepatitis (NASH), a common clinical disease, is becoming a leading cause of hepatocellular carcinoma (HCC). Dual specificity phosphatase 22 (DUSP22, also known as JKAP or JSP-1) expressed in...
-
Article
Open AccessThe E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes
Systemic metabolic syndrome significantly increases the risk of morbidity and mortality in patients with non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). However, no effectiv...
-
Article
One-step synthesis of thermally stable artificial multienzyme cascade system for efficient enzymatic electrochemical detection
Recently, metal-organic framework (MOF)-based multienzyme systems integrating different functional natural enzymes and/or nanomaterial-based artificial enzymes are attracting increasing attention due to their ...
-
Article
N-doped carbon shell encapsulated PtZn intermetallic nanoparticles as highly efficient catalysts for fuel cells
The high cost and poor durability of Pt nanoparticles (NPs) have always been great challenges to the commercialization of proton exchange membrane fuel cells (PEMFCs). Pt-based intermetallic NPs with a highly ...
-
Chapter and Conference Paper
Drug-Target Interaction Network Predictions for Drug Repurposing Using LASSO-Based Regularized Linear Classification Model
It has been well-known that biological and experimental methods for drug discovery are time-consuming and expensive. New efforts have been explored to perform drug repurposing through predicting drug-target in...
-
Article
Open AccessInflating hollow nanocrystals through a repeated Kirkendall cavitation process
The Kirkendall effect has been recently used to produce hollow nanostructures by taking advantage of the different diffusion rates of species involved in the chemical transformations of nanoscale objects. Here...
-
Article
Novel hydrogen storage properties of palladium nanocrystals activated by a pentagonal cyclic twinned structure
Researchers appear to have neglected a special form of crystallites, pentagonal cyclic twinning, in which an obvious two-dimensional lattice expansion exists leading to novel physical–chemical properties assoc...
-
Article
Morphology evolution of NaTaO3 submicrometer single-crystals: from cubes to quasi-spheres
Surface structure control of functional nano-/micro-crystallites has attracted great attention because many important physicochemical properties depend on their surface. Guided by the supersaturation-dependent...
-
Article
Open AccessSurface Structure Dependent Electrocatalytic Activity of Co3O4 Anchored on Graphene Sheets toward Oxygen Reduction Reaction
Catalytic activity is primarily a surface phenomenon, however, little is known about Co3O4 nanocrystals in terms of the relationship between the oxygen reduction reaction (ORR) catalytic activity and surface stru...
-
Article
Hierarchical WO3 flowers comprising porous single-crystalline nanoplates show enhanced lithium storage and photocatalysis
We report a morphology-conserved transformation approach to successfully synthesize a unique porous WO3 nanoplate assembly, which is hierarchically structured like a flower, from an ammonium tungsten peroxo oxala...
-
Article
Synthesis of spatially uniform metal alloys nanocrystals via a diffusion controlled growth strategy: The case of Au-Pd alloy trisoctahedral nanocrystals with tunable composition
Rational synthesis of bimetallic alloy nanocrystals (NCs) is still a great challenge. Especially, spatially uniform alloy NCs are very difficult to achieve because of the different reduction rates of the indiv...
-
Article
Facile syntheses and enhanced electrocatalytic activities of Pt nanocrystals with {hkk} high-index surfaces
Platinum (Pt) is an outstanding catalyst for many important industrial products. Because of its high cost and scarce reserves, it is very important to improve the performance of Pt catalysts. As the metal nano...
-
Protocol
A Single SnO2 Nanowire-Based Microelectrode
SnO2 nanowires are synthesized via the chemical-vapor-deposition process using gold as the catalyst and characterized by X-ray powder diffraction, field-emission scanning electron microscopy, high-resolution tran...
