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  1. Article

    Open Access

    The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes

    Systemic metabolic syndrome significantly increases the risk of morbidity and mortality in patients with non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). However, no effectiv...

    Minxuan Xu, Jun Tan, Wei Dong, Benkui Zou, Xuepeng Teng… in Nature Communications (2022)

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  2. No Access

    Article

    Pretreatment PET/CT imaging of angiogenesis based on 18F-RGD tracer uptake may predict antiangiogenic response

    To explore the relationship between metabolic uptake of the 18F-ALF-NOTA-PRGD2 (18F-RGD) tracer on positron emission tomography/computerized tomography (PET/CT) and the antiangiogenic effect of apatinib in patien...

    Li Li, Li Ma, Dong** Shang, Zhiguo Liu… in European Journal of Nuclear Medicine and M… (2019)

  3. Article

    Open Access

    18F-alfatide PET/CT may predict short-term outcome of concurrent chemoradiotherapy in patients with advanced non-small cell lung cancer

    The study aims to investigate the role of 18F-alfatide positron emission tomography/computed tomography (PET/CT) in predicting the short-term outcome of concurrent chemoradiotherapy (CCRT) in patients with advanc...

    **aohui Luan, Yong Huang, Song Gao… in European Journal of Nuclear Medicine and M… (2016)

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  4. No Access

    Article

    MiR-140-3p suppressed cell growth and invasion by downregulating the expression of ATP8A1 in non-small cell lung cancer

    MicroRNAs (miRNAs) as a class of small noncoding RNA molecules regulate the expression of targeted gene. The dysregulation of microRNAs is reported to be involved in carcinogenesis and tumor progression. Here,...

    Wei Dong, Chun** Yao, Xuepeng Teng, Jie Chai, **nhua Yang, Baosheng Li in Tumor Biology (2016)

  5. No Access

    Article

    A pilot study imaging integrin αvβ3 with RGD PET/CT in suspected lung cancer patients

    Angiogenesis is an essential step in tumour development and metastasis. Integrin αvβ3 plays a major role in angiogenesis, tumour growth and progression. A new tracer, 18F-AL-NOTA-PRGD2, denoted as 18F-alfatide, h...

    Song Gao, Honghu Wu, Wenwu Li, Shuqiang Zhao… in European Journal of Nuclear Medicine and M… (2015)