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Article
Open AccessAMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
The shift of carbon utilization from primarily glucose to other nutrients is a fundamental metabolic adaptation to cope with decreased blood glucose levels and the consequent decline in glucose oxidation. AMP-...
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Article
Open AccessMulti-agent system-based polymorphic distributed energy management for ships entering and leaving ports considering computing power resources
In order to realize the intelligent energy management of the complex ship energy system, achieve the carbon peaking and carbon neutrality goal and reduce the ship carbon emissions and ship operating costs, thi...
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Article
A multivariate model based on gadoxetic acid-enhanced MRI using Li-RADS v2018 and other imaging features for preoperative prediction of dual‑phenotype hepatocellular carcinoma
To investigate the diagnostic value of liver imaging reporting and data system (LI-RADS) v2018 and other imaging features in dual-phenotype hepatocellular carcinoma (DPHCC), establish a prediagnostic model bas...
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Article
Cystine-assisted accumulation of gold nanoparticles on ZnO to construct a sensitive surface-enhanced Raman spectroscopy substrate
Recently, various semiconductor/metal composites have been developed to fabricate surface-enhanced Raman spectroscopy substrates. However, low metal loading on semiconductors is still a challenge. In this stud...
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Article
Open AccessFunctional investigation of SLC1A2 variants associated with epilepsy
Epilepsy is a common neurological disorder and glutamate excitotoxicity plays a key role in epileptic pathogenesis. Astrocytic glutamate transporter GLT-1 is responsible for preventing excitotoxicity via clear...
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Article
Open AccessThe aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
The activity of 5′-adenosine monophosphate-activated protein kinase (AMPK) is inversely correlated with the cellular availability of glucose. When glucose levels are low, the glycolytic enzyme aldolase is not ...
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Article
Development of SERS-based immunoassay for the detection of cryptococcosis biomarker
The surface-enhanced Raman scattering (SERS) technique has displayed a broad application prospect in disease diagnosis owing to its high sensitivity, fast responsiveness, and high specificity. In this study, ...
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Article
Open AccessLow-dose metformin targets the lysosomal AMPK pathway through PEN2
Metformin, the most prescribed antidiabetic medicine, has shown other benefits such as anti-ageing and anticancer effects1–4. For clinical doses of metformin, AMP-activated protein kinase (AMPK) has a major role ...
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Article
Transaxillary Endoscopic Approach to Capsular Contracture Following Previous Breast Augmentation: Operative Technique and Clinical Outcome
Capsular contracture (CC) is a complication of breast augmentation that frequently requires revision surgery. The axillary approach reduces the visibility of the postoperative scar. It is unclear whether the p...
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Article
Synthesis and characterization of deep eutectic solvents (five hydrophilic and three hydrophobic), and hydrophobic application for microextraction of environmental water samples
Hydrophilic and hydrophobic deep eutectic solvents (DESs) as “green” solvents were applied in this study for the microextraction of environmental samples. A series of DESs (five hydrophilic and three hydrophob...
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Article
A novel acrylamide modified primary-secondary amine analogue as impurities remover for determination of carbendazim and dimethyl phthalate in apples
A novel acrylamide modified Primary-Secondary Amine (PSA) analogue (acrylamide/3-aminopropyltriethoxysilane/ silica) was prepared and used as impurities remover for pesticide residues (carbendazim and dimethyl...
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Article
Open AccessSource-Adaptation-Based Wireless Video Transport: A Cross-Layer Approach
Real-time packet video transmission over wireless networks is expected to experience bursty packet losses that can cause substantial degradation to the transmitted video quality. In wireless networks, channel ...
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Article
Open AccessCross-Layer QoS Control for Video Communications over Wireless Ad Hoc Networks
Assuming a wireless ad hoc network consisting of homogeneous video users with each of them also serving as a possible relay node for other users...
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Article
Enabling Real-Time H.264 Video Services over Wireless Ad Hoc Networks Using Joint Admission and Transmission Power Control
In a wireless ad hoc network, packets are sent from node-to-node in a multihop fashion until they reach the destination. In this paper we investigate the capacity of a wireless ad hoc network in supporting pa...
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Article
Solubilization of Synthetic Perfumes by Nonionic Surfactants and by Sulfoalkyl Ether β-CDs
Head-space gas chromatography has been used to study thesolubilization of synthetic perfumes by nonionic surfactants and by sulfoalkyl etherβ-cyclodextrins. This study shows that the addition of nonionic surfa...
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Article
Sulfoalkyl Ether β-Cyclodextrin Derivatives: Synthesis and Characterizations
A series of sulfoalkyl ether β-cyclodextrin derivatives, including sulfoethyl, sulfopropyl and sulfobutyl ethyl β-cyclodextrins, have been synthesized and characterized. Each sulfoalkyl ether β-cyclodextrin is...
