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Article
Streamlining Food Effect Assessment — Are Repeated Food Effect Studies Needed? An IQ Analysis
Current regulatory guidelines on drug-food interactions recommend an early assessment of food effect to inform clinical dosing instructions, as well as a pivotal food effect study on the to-be-marketed formula...
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Article
Open AccessRole of miR-182/PDCD4 axis in aggressive behavior of prostate cancer in the African Americans
Prostate cancer is one of the most commonly diagnosed cancers among men. African Americans (AA) are at an increased risk of develo** prostate cancer compared to European Americans (EA). miRNAs play a critica...
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Article
Correction to: Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective
An Erratum to this paper has been published: https://doi.org/10.1208/s12248-020-00535-z
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Article
Open AccessUse of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective
The effect of food on pharmacokinetic properties of drugs is a commonly observed occurrence affecting about 40% of orally administered drugs. Within the pharmaceutical industry, significant resources are inves...