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  1. No Access

    Article

    Role of CRISPR/Cas9 based therapy in breast cancer: a future direction

    Breast cancer, a prominent contributor to global cancer-related deaths, is a substantial health obstacle for women. Of all the several types of breast cancers, invasive ductal carcinoma is the most prevalent h...

    Asim Asrar, Deepika Gupta, Pooja Sharma, Sanjit Kumar Agarwal… in The Nucleus (2024)

  2. No Access

    Article

    Gene editing and therapy in acquired and inherited cardiovascular disorders

    Gene editing and therapy holds immense promise in addressing cardiovascular disorders by enabling precise modifications to the genetic groundworks of these conditions. This technology offers a targeted approac...

    Sushmitha Duddu, Rituparna Chakrabarti, Pooja Sharma, Deepika Gupta… in The Nucleus (2024)

  3. No Access

    Chapter

    Regeneration and Tissue Microenvironment

    The human body is composed of trillions of cells, which, despite sharing the same genetic material, differentiate into different cell types. For a long time, scientists have been fascinated by the enigma of ce...

    Sushmitha Duddu, Anindita Bhattacharya, Rituparna Chakrabarti… in Regenerative Medicine (2023)

  4. No Access

    Book

    Regenerative Medicine

    Emerging Techniques to Translation Approaches

    Nishant Chakravorty, Praphulla Chandra Shukla (2023)

  5. No Access

    Chapter

    Stem Cells and Therapies in Cardiac Regeneration

    Ischemic heart diseases (IHD) are a significant cause of death all over the world increasing the cardiovascular disease (CVD) burden. Blockade of coronary arteries followed by an infarct in the heart is the ba...

    Harshavardhan Renikunta, Rituparna Chakrabarti, Sushmitha Duddu… in Regenerative Medicine (2023)

  6. No Access

    Article

    Exploring the crosstalk between long non-coding RNAs and microRNAs to unravel potential prognostic and therapeutic biomarkers in β-thalassemia

    β-thalassemia is a prevalent monogenic disorder characterized by reduced or absent synthesis of the β-globin chain. Although great effort has been made to ameliorate the disease severity of β-thalassemic patie...

    Motiur Rahaman, Mandrita Mukherjee, Shatarupa Bhattacharya… in Molecular Biology Reports (2022)

  7. No Access

    Article

    Revisiting fetal hemoglobin inducers in beta-hemoglobinopathies: a review of natural products, conventional and combinatorial therapies

    Beta-hemoglobinopathies exhibit a heterogeneous clinical picture with varying degrees of clinical severity. Pertaining to the limited treatment options available, where blood transfusion still remains the comm...

    Mandrita Mukherjee, Motiur Rahaman, Suman Kumar Ray… in Molecular Biology Reports (2022)

  8. Article

    Open Access

    Inadvertent nucleotide sequence alterations during mutagenesis: highlighting the vulnerabilities in mouse transgenic technology

    In the last three decades, researchers have utilized genome engineering to alter the DNA sequence in the living cells of a plethora of organisms, ranging from plants, fishes, mice, to even humans. This has bee...

    Anuran Ghosh, Rituparna Chakrabarti… in Journal of Genetic Engineering and Biotech… (2021)

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