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  1. Article

    Open Access

    Inadvertent nucleotide sequence alterations during mutagenesis: highlighting the vulnerabilities in mouse transgenic technology

    In the last three decades, researchers have utilized genome engineering to alter the DNA sequence in the living cells of a plethora of organisms, ranging from plants, fishes, mice, to even humans. This has bee...

    Anuran Ghosh, Rituparna Chakrabarti… in Journal of Genetic Engineering and Biotech… (2021)

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    Article

    Ectopic release of nitric oxide modulates the onset of cardiac development in avian model

    Heart development is one of the earliest developmental events, and its pum** action is directly linked to the intensity of development of other organs. Heart contractions mediate the circulation of the nutri...

    Pavitra Kumar, Anuran Ghosh… in In Vitro Cellular & Developmental Biology … (2020)

  3. No Access

    Article

    Thalidomide remodels develo** heart in chick embryo: discovery of a thalidomide mediated hematoma in heart muscle

    Despite of medical disaster caused by thalidomide in 1960s, the drug came to clinical use again for the treatment of erythema nodosum leprosum (ENL) and multiple myeloma. Recently, a new generation of children...

    Pavitra Kumar, Harish A. Kumar… in Naunyn-Schmiedeberg's Archives of Pharmaco… (2018)