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Alveolar Cleft Reconstruction
Bone grafting of the clefted alveolus is indicated to main the transverse dimension of the maxillary alveolar ridge, to give support to the nasal ala, and to provide a healthy periodontium for natural dental e...
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Article
Open AccessCRISPR interference to interrogate genes that control biofilm formation in Pseudomonas fluorescens
Bacterial biofilm formation involves signaling and regulatory pathways that control the transition from motile to sessile lifestyle, production of extracellular polymeric matrix, and maturation of the biofilm ...
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Article
Open AccessThe lichen symbiosis re-viewed through the genomes of Cladonia grayi and its algal partner Asterochloris glomerata
Lichens, encompassing 20,000 known species, are symbioses between specialized fungi (mycobionts), mostly ascomycetes, and unicellular green algae or cyanobacteria (photobionts). Here we describe the first para...
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Article
Open AccessPseudomonas fluorescens increases mycorrhization and modulates expression of antifungal defense response genes in roots of aspen seedlings
Plants, fungi, and bacteria form complex, mutually-beneficial communities within the soil environment. In return for photosynthetically derived sugars in the form of exudates from plant roots, the microbial sy...
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Statistical Tools for Study Design: Replication
The ability to collect massive amounts of data relevant to hydrocarbon microbiology from marine and terrestrial environments continues to grow. Given the potential expense and effort of collecting this data ho...
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Article
Open AccessMetabolome of human gut microbiome is predictive of host dysbiosis
Humans live in constant and vital symbiosis with a closely linked bacterial ecosystem called the microbiome, which influences many aspects of human health. When this microbial ecosystem becomes disrupted, the ...
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Chapter
Carbon Sequestration
With the rising levels of atmospheric carbon dioxide (CO2) threatening to alter global climate, carbon sequestration in plants has been proposed as a possible moderator or solution to the problem. This chapter ex...
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Article
Open AccessBowStrap v1.0: Assigning statistical significance to expressed genes using short-read transcriptome data
Background: Deep RNA sequencing, the application of Next Generation sequencing technology to generate a comprehensive profile of the message RNA present in a set of biological samples, provides unprecedented r...
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Article
Predicting bacterial community assemblages using an artificial neural network approach
Microbial Assemblage Prediction is a predictive model for the climate-dependent abundance of microbial taxa in space and time. It takes potential interactions between taxa into account and is used on longitudi...
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Article
Open AccessPredicted Relative Metabolomic Turnover (PRMT): determining metabolic turnover from a coastal marine metagenomic dataset
The world's oceans are home to a diverse array of microbial life whose metabolic activity helps to drive the earth's biogeochemical cycles. Metagenomic analysis has revolutionized our access to these communiti...
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Article
Open AccessUsing next generation transcriptome sequencing to predict an ectomycorrhizal metabolome
Mycorrhizae, symbiotic interactions between soil fungi and tree roots, are ubiquitous in terrestrial ecosystems. The fungi contribute phosphorous, nitrogen and mobilized nutrients from organic matter in the so...
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Article
Open AccessDistribution of Anthocyanins Delivered from a Bioadhesive Black Raspberry Gel Following Topical Intraoral Application in Normal Healthy Volunteers
Results from our oral cavity chemoprevention trial demonstrated appreciable interpatient variations regarding chemopreventive efficacy of a freeze dried black raspberry (FBR) gel. We speculated these data refl...
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Formulation and In-Vitro and In-Vivo Evaluation of a Mucoadhesive Gel Containing Freeze Dried Black Raspberries: Implications for Oral Cancer Chemoprevention
The purpose of these studies was to formulate mucoadhesive gels containing freeze dried black raspberries (FBR) and to determine optimum parameters for a subset of FBR bioactive compounds including anthocyanin...
