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Article
Understanding the risks of co-exposures in a changing world: a case study of dual monitoring of the biotoxin domoic acid and Vibrio spp. in Pacific oyster
Assessing the co-occurrence of multiple health risk factors in coastal ecosystems is challenging due to the complexity of multi-factor interactions and limited availability of simultaneously collected data. Un...
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Article
Open AccessSodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner
It has recently become well-established that there is a connection between Alzheimer’s disease pathology and gut microbiome dysbiosis. We have previously demonstrated that antibiotic-mediated gut microbiota pe...
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Article
Genomic and Phenotypic Insight into the Probiotic Potential of Lactic Acid Bacterial spp. Associated with the Human Gut Mucosa
Commensal microbiome-based health support is gaining respect in the medical community and new human gut-associated Lactic Acid Bacteria (LAB) strains must be evaluated for their probiotic potential. Here we ch...
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Article
Open AccessGut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: the METS-microbiome study
The relationship between microbiota, short chain fatty acids (SCFAs), and obesity remains enigmatic. We employ amplicon sequencing and targeted metabolomics in a large (n = 1904) African origin cohort from Ghana,...
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Article
Open AccessMulti-level analysis of the gut–brain axis shows autism spectrum disorder-associated molecular and microbial profiles
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut–brain axis (GBA) has been implicated in...
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Article
Plant and fungal species interactions differ between aboveground and belowground habitats in mountain forests of eastern China
Plant and fungal species interactions drive many essential ecosystem properties and processes; however, how these interactions differ between aboveground and belowground habitats remains unclear at large spati...
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Article
Open AccessPlasma metabolites with mechanistic and clinical links to the neurovascular disease cavernous angioma
Cavernous angiomas (CAs) affect 0.5% of the population, predisposing to serious neurologic sequelae from brain bleeding. A leaky gut epithelium associated with a permissive gut microbiome, was identified in pa...
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Article
Open AccessMicrobiome response in an urban river system is dominated by seasonality over wastewater treatment upgrades
Microorganisms such as coliform-forming bacteria are commonly used to assess freshwater quality for drinking and recreational use. However, such organisms do not exist in isolation; they exist within the conte...
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Article
Open AccessInteractions between perceived stress and microbial-host immune components: two demographically and geographically distinct pregnancy cohorts
Higher stress during pregnancy associates with negative outcomes and elevated inflammation. The gut microbiota, reflecting environment and social interactions, alongside host immune responses have the potentia...
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Article
Open AccessStandardized multi-omics of Earth’s microbiomes reveals microbial and metabolite diversity
Despite advances in sequencing, lack of standardization makes comparisons across studies challenging and hampers insights into the structure and function of microbial communities across multiple habitats on a ...
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Article
Triclosan-containing sutures: safety and resistance issues need to be addressed prior to generalized use
Triclosan (TCS), a synthetic antimicrobial, has been incorporated into a variety of personal care products worldwide. Since 2016, upon the recommendation of World Health Organization (WHO), the use of TCS-cont...
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Article
Multi-omics analyses of airway host–microbe interactions in chronic obstructive pulmonary disease identify potential therapeutic interventions
The mechanistic role of the airway microbiome in chronic obstructive pulmonary disease (COPD) remains largely unexplored. We present a landscape of airway microbe–host interactions in COPD through an in-depth ...
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Article
Correction to: Precision medicine in perinatal depression in light of the human microbiome
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Article
Synchrony and idiosyncrasy in the gut microbiome of wild baboons
Human gut microbial dynamics are highly individualized, making it challenging to link microbiota to health and to design universal microbiome therapies. This individuality is typically attributed to variation ...
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Article
Open AccessThe impact of maternal asthma on the preterm infants' gut metabolome and microbiome (MAP study)
Preterm infants are at a greater risk for the development of asthma and atopic disease, which can lead to lifelong negative health consequences. This may be due, in part, to alterations that occur in the gut m...
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Article
Open AccessCorrection to: The chemodiversity of paddy soil dissolved organic matter correlates with microbial community at continental scales
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessChemical composition of material extractives influences microbial growth and dynamics on wetted wood materials
The impact of material chemical composition on microbial growth on building materials remains relatively poorly understood. We investigate the influence of the chemical composition of material extractives on m...
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Article
Implication of gut microbiota in the association between infant antibiotic exposure and childhood obesity and adiposity accumulation
In animal studies early life antibiotic exposure causes metabolic abnormalities including obesity through microbiota disruption, but evidence from human studies is scarce. We examined involvement of gut microb...
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Article
Open AccessEarth microbial co-occurrence network reveals interconnection pattern across microbiomes
Microbial interactions shape the structure and function of microbial communities; microbial co-occurrence networks in specific environments have been widely developed to explore these complex systems, but thei...
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Article
Open AccessPermissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma
Cavernous angiomas (CA) are common vascular anomalies causing brain hemorrhage. Based on mouse studies, roles of gram-negative bacteria and altered intestinal homeostasis have been implicated in CA pathogenesi...
