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Article
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer
Metastasis occurs frequently after resection of pancreatic cancer (PaC). In this study, we hypothesized that multi-parametric analysis of pre-metastatic liver biopsies would classify patients according to thei...
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Article
Open AccessAdapted forest management to improve the potential for reindeer husbandry in Northern Sweden
In northern Sweden, improvements of grazing conditions are necessary for the continuation of traditional, natural pasture-based reindeer husbandry. Ground and tree lichen constitute the main fodder resource fo...
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Article
Open AccessReal-world patient characteristics associated with survival of 2 years or more after radium-223 treatment for metastatic castration-resistant prostate cancer (EPIX study)
The real-world EPIX study was conducted to gather information about the characteristics of patients with metastatic castration-resistant prostate cancer (mCRPC) who survived ≥2 years after treatment with the a...
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Article
Open AccessAspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial
Colorectal cancer is one the most common cancers in the western world with increasing incidence. Approximately 50% of the patients develop liver metastases. Resection of liver metastases is the treatment of ch...
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Article
Portal vein embolization with N-butyl cyanoacrylate glue is superior to other materials: a systematic review and meta-analysis
It remains uncertain which embolization material is best for portal vein embolization (PVE). We investigated the various materials for effectiveness in inducing future liver remnant (FLR) hypertrophy, technica...
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Article
Open AccessDisease prevalence and number of health care visits among members of a nationwide sports organization compared to matched controls
Physical activity has positive effects on several diseases and may reduce the risk of morbidity and the mortality rate. Whether the prevalence of disease and health care consumption differ between the members ...
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Article
Open AccessOutcomes of Simultaneous Resections and Classical Strategy for Synchronous Colorectal Liver Metastases in Sweden: A Nationwide Study with Special Reference to Major Liver Resections
About 20% of patients with colorectal cancer have liver metastases at the time of diagnosis, and surgical resection offers a chance for cure. The aim of the present study was to compare outcomes for patients t...
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Article
Open AccessDigital twins to personalize medicine
Personalized medicine requires the integration and processing of vast amounts of data. Here, we propose a solution to this challenge that is based on constructing Digital Twins. These are high-resolution model...
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Article
Open Access‘I want to know why and need to be involved in my own care…’: a qualitative interview study with liver, bile duct or pancreatic cancer patients about their experiences with involvement in care
Patients’ involvement in their own care is important for those with upper abdominal tumours. Care is often conducted according to standardized fast-track care programs (FTCP), and a shorter hospital stay is on...
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Article
Open AccessLaparoscopic versus open distal pancreatectomy (LAPOP): study protocol for a single center, nonblinded, randomized controlled trial
Earlier nonrandomized studies have suggested that laparoscopic distal pancreatectomy (LDP) is advantageous compared with open distal pancreatectomy (ODP) regarding hospital stay, blood loss, and recovery. Only...
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Article
Open AccessFuture Liver Remnant (FLR) Increase in Patients with Colorectal Liver Metastases Is Highest the First Week After Portal Vein Occlusion
Portal vein occlusion (PVO) is an established method to increase the volume of the future liver remnant (FLR). The main reasons for not proceeding to radical hepatectomy are lack of volume increase and tumor p...
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Article
Open AccessA minority-group of renal cell cancer patients with high infiltration of CD20+B-cells is associated with poor prognosis
The role of B-lymphocytes in solid tumours is unclear. Tumour biology studies have implied both anti- and pro-tumoural effects and prognostic studies have mainly linked B-cells to increased survival. This stud...
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Article
Open AccessAre Incidental Gallbladder Cancers Missed with a Selective Approach of Gallbladder Histology at Cholecystectomy?
Incidental gallbladder cancer (IGBC) is an unexpected finding when a cholecystectomy is performed upon a benign indication, and the use of routine or selective histological analysis of gallbladder specimen is ...
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Chapter
Laparoscopic Distal Pancreatectomy: How I Do It
After the widespread introduction of laparoscopic surgery being more and more frequently applied to both benign and malignant lesions, this technique has now become the golden standard for benign and premalign...
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Article
Open AccessPerivascular PDGFR-β is an independent marker for prognosis in renal cell carcinoma
Renal cell carcinoma (RCC) is a highly vascularised tumour, where anti-angiogenic treatment with multi-tyrosine-kinase-inhibitor, is used for first-line treatment of metastatic disease. Variations in vascular ...
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Chapter
Multi-level Planning and Conflicting Interests in the Forest Landscape
This chapter describes and analyses overlap** planning structures and multi-level planning issues and how they affect current land use and management in the forest landscape. Forest land use in Sweden is bas...
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Chapter
Interactions Between Forest Owners and Their Forests
More than half of the forest land in Europe is privately owned, and ownership structure is known to have implications for management, production of timber and other forest products and services that support th...
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Article
On the decline of ground lichen forests in the Swedish boreal landscape: Implications for reindeer husbandry and sustainable forest management
Lichens are a bottleneck resource for circumpolar populations of reindeer, and as such, for reindeer husbandry as an indigenous Sami land-use tradition in northern Sweden. This study uses ground lichen data an...
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Article
Open AccessFrom palliative to curative treatment - stage IV mucinous adenocarcinoma, successfully treated with metronomic capecitabine in combination with Bevacizumab and surgery- a case report
Mucinous adenocarcinoma (MAC) represents 6-19 % of all colorectal carcinoma. It is associated with poorer response to chemotherapy and chemoradiotherapy.
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Article
Open AccessWind farm construction impacts reindeer migration and movement corridors
Over the last decade, we have seen a massive increase in the construction of wind farms in northern Fennoscandia. Wind farms comprising hundreds of wind turbines are being built, with little knowledge of the p...
