6 Result(s)
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Per M. Ueland
Internal Medicine
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Article
Open AccessAssociations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study
Studies investigating associations between kynurenines and cognitive function have generally been small, restricted to clinical samples or have found inconsistent results, and associations in the general adult...
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Article
Open AccessThe kynurenine:tryptophan ratio as a predictor of incident type 2 diabetes mellitus in individuals with coronary artery disease
The tryptophan metabolite kynurenine has potent immune modulatory and vasoactive properties. Experimental data implicate kynurenine in obesity-related morbidities. Epidemiological studies are, however, sparse....
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Article
Open AccessTryptophan catabolism and immune activation in primary and chronic HIV infection
Kynurenine/Tryptophan ratio (KTR) is increased in HIV infection, and linked to immune activation. We hypothesized that early cART initiation results in lower KTR compared to late initiation. Furthermore, we hy...
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Chapter
The Hordaland Homocysteine Study: Lifestyle and Total Plasma Homocysteine in Western Norway
The Hordaland Homocysteine Study is a cohort of approximately 18,000 men and women, ages 40–67, who had their total plasma homocysteine (tHcy) determined in 1992 or 1993. The long-term aim of the study is to r...
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Chapter
On the Formation and Fate of Total Plasma Homocysteine
The total concentration of homocysteine (tHcy)* in plasma is a useful marker of impaired function of cobalamin and folate. Moreover, it is an independent risk factor for atherosclerotic disease [1]. These find...
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Chapter
Homocysteine and Drug Therapy
Several agents other than vitamins involved in homocysteine (Hcy) metabolism affect plasma homocysteine (tHcy) total concentration. The mechanisms behind the hyperhomocysteinemia vary from altered homocysteine...
