Skip to main content

and
  1. No Access

    Article

    Complete miscibility of immiscible elements at the nanometre scale

    Understanding the mixing behaviour of elements in a multielement material is important to control its structure and property. When the size of a multielement material is decreased to the nanoscale, the miscibi...

    Peng-Cheng Chen, Mengyu Gao, Caitlin A. McCandler, Chengyu Song in Nature Nanotechnology (2024)

  2. No Access

    Article

    Active hole formation in epithelioid tissues

    The formation of holes in epithelial tissue is essential for development, but it can also be associated with epithelial barrier dysfunction and cancer progression. Here we show that active cell contraction in ...

    Jian-Qing Lv, Peng-Cheng Chen, Yun-** Chen, Hao-Yu Liu, Shi-Da Wang in Nature Physics (2024)

  3. No Access

    Article

    Targeting ONECUT3 blocks glycolytic metabolism and potentiates anti-PD-1 therapy in pancreatic cancer

    Reprogramming glucose metabolism, also known as the Warburg effect (aerobic glycolysis), is a hallmark of cancers. Increased tumor glycolysis not only favors rapid cancer cell proliferation but reprograms the ...

    Peng-Cheng Chen, Yong Ning, Hui Li, **-Gen Su, Jiang-Bo Shen in Cellular Oncology (2024)

  4. No Access

    Article

    Characterizing mechanical properties of epithelial monolayers based on indentation

    Epithelial tissues have a variety of functions, such as protection, secretion, and absorption. Appropriate mechanical properties of epithelia are essential to achieve these functions. Based on the indentation ...

    **g-Yi Li, Peng-Cheng Chen, Shao-Zhen Lin in The European Physical Journal Special Topi… (2023)

  5. No Access

    Article

    Immobilization of Actinobacillus succinogenes on nano- and micro-fiber membranes for efficient and robust production of succinic acid

    This work aimed to study the efficiency of nano- and micro- fiber membranes in immobilizing Actinobacillus succinogenes CCTCC M2012036 for succinic acid production. Among the four kinds of electrospun nanofiber m...

    Peng-Cheng Chen, Yao-Dan Zhang, **ang-Yu Ye in Bioprocess and Biosystems Engineering (2023)

  6. No Access

    Article

    Operando studies reveal active Cu nanograins for CO2 electroreduction

    Carbon dioxide electroreduction facilitates the sustainable synthesis of fuels and chemicals1. Although Cu enables CO2-to-multicarbon product (C2+) conversion, the nature of the active sites under operating condi...

    Yao Yang, Sheena Louisia, Sunmoon Yu, Jianbo **, Inwhan Roh, Chubai Chen in Nature (2023)

  7. No Access

    Article

    Exploration of the bio-analogous asymmetric C–C coupling mechanism in tandem CO2 electroreduction

    C–C coupling is a critical step of CO2 fixation in constructing the carbon skeleton of value-added multicarbon products. The Wood–Ljungdahl pathway is an efficient natural process through which microbes transform...

    Chubai Chen, Sunmoon Yu, Yao Yang, Sheena Louisia, Inwhan Roh in Nature Catalysis (2022)

  8. No Access

    Article

    Collective migrations in an epithelial–cancerous cell monolayer

    Collective cell migration is extensively observed in embryo development and cancer invasion. During these processes, the interactions between cells with distinct identities and fates are of importance for boun...

    Jian-Qing Lv, Peng-Cheng Chen, Liu-Yuan Guan, Wojciech T. Góźdź in Acta Mechanica Sinica (2021)

  9. Article

    Open Access

    Predicted functional interactome of Caenorhabditis elegans and a web tool for the functional interpretation of differentially expressed genes

    The nematode worm, Caenorhabditis elegans, is a saprophytic species that has been emerging as a standard model organism since the early 1960s. This species is useful in numerous fields, including developmental bi...

    Peng-Cheng Chen, Li Ruan, Jie **, Yu-Tian Tao, **ao-Bao Ding in Biology Direct (2020)

  10. Article

    Open Access

    Colloidal crystal engineering with metal–organic framework nanoparticles and DNA

    Colloidal crystal engineering with nucleic acid-modified nanoparticles is a powerful way for preparing 3D superlattices, which may be useful in many areas, including catalysis, sensing, and photonics. To date,...

    Shunzhi Wang, Sarah S. Park, Cassandra T. Buru, Haixin Lin in Nature Communications (2020)

  11. No Access

    Article

    A tri-layer approach to controlling nanopore formation in oxide supports

    A novel tri-layer approach for immobilizing metal nanoparticles in SiO2 supports is presented. In this work, we show that under rapid heating to temperatures of approximately 1,000 °C, metal nanoparticles less th...

    Abha A. Gosavi, James L. Hedrick, Peng-Cheng Chen, Justin M. Notestein in Nano Research (2019)

  12. No Access

    Article

    Construction of fibrous bed bioreactor for enhanced succinic acid production using wastewater of dextran fermentation

    A new applicability of wastewater of dextran fermentation (WWDF) for biological production of succinic acid with A. succinogenes CCTCC M2012036 was reported in this work for the first time. Notably, K2CO3 was use...

    Peng-cheng Chen, **n-hua Zha, Pu Zheng in Bioprocess and Biosystems Engineering (2017)

  13. No Access

    Article

    Utilization of a biphasic oil/aqueous cellulose nanofiber membrane bioreactor with immobilized lipase for continuous hydrolysis of olive oil

    A simple method is proposed to fabricate a biphasic lipase-immobilized cellulose membrane bioreactor with high enzyme loading and activity retention. This bioreactor was assembled with electrospun cellulose na...

    Peng-Cheng Chen, **ao-Jun Huang, Zhi-Kang Xu in Cellulose (2014)

  14. Article

    Open Access

    Mineral-Coated Polymer Membranes with Superhydrophilicity and Underwater Superoleophobicity for Effective Oil/Water Separation

    Oil-polluted water is a worldwide problem due to the increasing industrial oily wastewater and the frequent oil spill accidents. Here, we report a novel kind of superhydrophilic hybrid membranes for effective ...

    Peng-Cheng Chen, Zhi-Kang Xu in Scientific Reports (2013)

  15. No Access

    Article

    Immobilization of lipase onto cellulose ultrafine fiber membrane for oil hydrolysis in high performance bioreactor

    Practical application of biphasic enzyme-immobilized membrane bioreactors (EMBR) requires efficient loading of the enzyme with retention of enzymatic activity. Here, we report a method to fabricate an ultrafin...

    Peng-Cheng Chen, **ao-Jun Huang, Fu Huang, Yang Ou, Ming-Rui Chen, Zhi-Kang Xu in Cellulose (2011)