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Article
Complete miscibility of immiscible elements at the nanometre scale
Understanding the mixing behaviour of elements in a multielement material is important to control its structure and property. When the size of a multielement material is decreased to the nanoscale, the miscibi...
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Article
Active hole formation in epithelioid tissues
The formation of holes in epithelial tissue is essential for development, but it can also be associated with epithelial barrier dysfunction and cancer progression. Here we show that active cell contraction in ...
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Article
Targeting ONECUT3 blocks glycolytic metabolism and potentiates anti-PD-1 therapy in pancreatic cancer
Reprogramming glucose metabolism, also known as the Warburg effect (aerobic glycolysis), is a hallmark of cancers. Increased tumor glycolysis not only favors rapid cancer cell proliferation but reprograms the ...
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Article
Characterizing mechanical properties of epithelial monolayers based on indentation
Epithelial tissues have a variety of functions, such as protection, secretion, and absorption. Appropriate mechanical properties of epithelia are essential to achieve these functions. Based on the indentation ...
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Article
Immobilization of Actinobacillus succinogenes on nano- and micro-fiber membranes for efficient and robust production of succinic acid
This work aimed to study the efficiency of nano- and micro- fiber membranes in immobilizing Actinobacillus succinogenes CCTCC M2012036 for succinic acid production. Among the four kinds of electrospun nanofiber m...
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Article
Operando studies reveal active Cu nanograins for CO2 electroreduction
Carbon dioxide electroreduction facilitates the sustainable synthesis of fuels and chemicals1. Although Cu enables CO2-to-multicarbon product (C2+) conversion, the nature of the active sites under operating condi...
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Article
Exploration of the bio-analogous asymmetric C–C coupling mechanism in tandem CO2 electroreduction
C–C coupling is a critical step of CO2 fixation in constructing the carbon skeleton of value-added multicarbon products. The Wood–Ljungdahl pathway is an efficient natural process through which microbes transform...
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Article
Collective migrations in an epithelial–cancerous cell monolayer
Collective cell migration is extensively observed in embryo development and cancer invasion. During these processes, the interactions between cells with distinct identities and fates are of importance for boun...
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Article
Open AccessPredicted functional interactome of Caenorhabditis elegans and a web tool for the functional interpretation of differentially expressed genes
The nematode worm, Caenorhabditis elegans, is a saprophytic species that has been emerging as a standard model organism since the early 1960s. This species is useful in numerous fields, including developmental bi...
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Article
Open AccessColloidal crystal engineering with metal–organic framework nanoparticles and DNA
Colloidal crystal engineering with nucleic acid-modified nanoparticles is a powerful way for preparing 3D superlattices, which may be useful in many areas, including catalysis, sensing, and photonics. To date,...
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Article
A tri-layer approach to controlling nanopore formation in oxide supports
A novel tri-layer approach for immobilizing metal nanoparticles in SiO2 supports is presented. In this work, we show that under rapid heating to temperatures of approximately 1,000 °C, metal nanoparticles less th...
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Article
Construction of fibrous bed bioreactor for enhanced succinic acid production using wastewater of dextran fermentation
A new applicability of wastewater of dextran fermentation (WWDF) for biological production of succinic acid with A. succinogenes CCTCC M2012036 was reported in this work for the first time. Notably, K2CO3 was use...
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Article
Utilization of a biphasic oil/aqueous cellulose nanofiber membrane bioreactor with immobilized lipase for continuous hydrolysis of olive oil
A simple method is proposed to fabricate a biphasic lipase-immobilized cellulose membrane bioreactor with high enzyme loading and activity retention. This bioreactor was assembled with electrospun cellulose na...
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Article
Open AccessMineral-Coated Polymer Membranes with Superhydrophilicity and Underwater Superoleophobicity for Effective Oil/Water Separation
Oil-polluted water is a worldwide problem due to the increasing industrial oily wastewater and the frequent oil spill accidents. Here, we report a novel kind of superhydrophilic hybrid membranes for effective ...
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Article
Immobilization of lipase onto cellulose ultrafine fiber membrane for oil hydrolysis in high performance bioreactor
Practical application of biphasic enzyme-immobilized membrane bioreactors (EMBR) requires efficient loading of the enzyme with retention of enzymatic activity. Here, we report a method to fabricate an ultrafin...