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Article
Open AccessCorrection to: Post‑mortem changes of the vascular system—a thanatological study using multidetector computed tomography
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Article
Open AccessPost-mortem changes of the vascular system—a thanatological study using multidetector computed tomography
Forensic pathologists have to deal with post-mortem changes of the human body. Those post-mortem phenomena are familiar and largely described in thanatology. However, knowledge about the influence of post-mort...
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Chapter and Conference Paper
Digitalization of the Last Mile of a Humanitarian Supply Chain
The digitalization of humanitarian supply chains allows overcoming one of the greatest difficulties faced by NGOs and governments in managing health equipment in crisis situations: the visibility of stocks and...
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Article
The effect of vitamin B12 and folic acid supplementation on routine haematological parameters in older people: an individual participant data meta-analysis
Low vitamin B12 and folate levels in community-dwelling older people are usually corrected with supplements. However, the effect of this supplementation on haematological parameters in older persons is not kno...
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Article
The role of angiography in the congruence of cardiovascular measurements between autopsy and postmortem imaging
Postmortem CT angiography is the method of choice for the postmortem imaging investigations of the cardiovascular (CV) system. However, autopsy still remains the gold standard for CV measurement. Nevertheless,...
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Article
Open AccessThe trail making test as a screening instrument for driving performance in older drivers; a translational research
In many countries, primary care physicians determine whether or not older drivers are fit to drive. Little, however, is known regarding the effects of cognitive decline on driving performance and the means to ...
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Article
Erratum to: Postmortem computed tomography angiography vs. conventional autopsy: advantages and inconveniences of each method
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Article
Open AccessDevelopment of mental disorders one year after exposure to psychosocial stressors; a cohort study in primary care patients with a physical complaint
Mental disorders, common in primary care, are often associated with physical complaints. While exposure to psychosocial stressors and development or presence of principal mental disorders (i.e. depression, anx...
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Article
Open AccessDevelopment and validation of a clinical prediction rule for chest wall syndrome in primary care
Chest wall syndrome (CWS), the main cause of chest pain in primary care practice, is most often an exclusion diagnosis. We developed and evaluated a clinical prediction rule for CWS.
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Article
Evaluation of C-reactive protein, procalcitonin, tumor necrosis factor alpha, interleukin-6, and interleukin-8 as diagnostic parameters in sepsis-related fatalities
The aims of this study were to investigate the usefulness of serum C-reactive protein, procalcitonin, tumor necrosis factor alpha, interleukin-6, and interleukin-8 as postmortem markers of sepsis and to compar...
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Article
Is the formula of Traub still up to date in antemortem blood glucose level estimation?
According to the hypothesis of Traub, also known as the ‘formula of Traub’, postmortem values of glucose and lactate found in the cerebrospinal fluid or vitreous humor are considered indicators of antemortem b...
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Article
Open AccessClinical evaluation of iron treatment efficiency among non-anemic but iron-deficient female blood donors: a randomized controlled trial
Iron deficiency without anemia is related to adverse symptoms that can be relieved by supplementation. Since a blood donation can induce such an iron deficiency, we investigated the clinical impact of iron tre...
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Article
Distribution of artifactual gas on post-mortem multidetector computed tomography (MDCT)
We investigated the incidence and distribution of post-mortem gas detected with multidetector computed tomography (MDCT) to identify factors that could distinguish artifactual gas from cardiac air embolism.
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Article
Open AccessSensitivity and specificity of NT-proBNP to detect heart failure at post mortem examination
NT-proBNP, a marker of cardiac failure, has been shown to be stable in post mortem samples. The aim of this study was to assess the accuracy of NT-proBNP to detect heart failure in the forensic setting. One hu...
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Article
Open AccessThe 'help' question doesn't help when screening for major depression: external validation of the three-question screening test for primary care patients managed for physical complaints
Major depression, although frequent in primary care, is commonly hidden behind multiple physical complaints that are often the first and only reason for patient consultation. Major depression can be screened b...
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Article
Open AccessFramework for the impact analysis and implementation of Clinical Prediction Rules (CPRs)
Clinical Prediction Rules (CPRs) are tools that quantify the contribution of symptoms, clinical signs and available diagnostic tests, and in doing so stratify patients according to the probability of having a ...
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Article
Open AccessOral vitamin B12 for patients suspected of subtle cobalamin deficiency: a multicentre pragmatic randomised controlled trial
Evidence regarding the effectiveness of oral vitamin B12 in patients with serum vitamin B12 levels between 125-200 pM/l is lacking. We compared the effectiveness of one-month oral vitamin B12 supplementation i...
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Article
Open AccessPatients presenting with somatic complaints in general practice: depression, anxiety and somatoform disorders are frequent and associated with psychosocial stressors
Mental disorders in primary care patients are frequently associated with physical complaints that can mask the disorder. There is insufficient knowledge concerning the role of anxiety, depression, and somatofo...
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Article
Open AccessPredictive ability of an early diagnostic guess in patients presenting with chest pain; a longitudinal descriptive study
The intuitive early diagnostic guess could play an important role in reaching a final diagnosis. However, no study to date has attempted to quantify the importance of general practitioners' (GPs) ability to co...
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Article
A Health Behaviour Cross-Sectional Study of Immigrants and Non-immigrants in a Swiss Urban General-Practice Setting
Background Little is known about smoking, unhealthy use of alcohol, and risk behaviours for sexually transmitted diseases (STDs) in immigrants from developed and develo** countries. Method We performed a cross-...