-
Protocol
Neural Endophenotype Assessment in Zebrafish Larvae Using Optomotor and ZebraBox Locomotion Assessment
Due to the highly conserved genetics across the central nervous system, the easily probed visual system can act as an endophenotype for assessing neurological function. Here, we describe a psychophysics approa...
-
Article
Open AccessExperience-dependent development of visual sensitivity in larval zebrafish
The zebrafish (Danio rerio) is a popular vertebrate model for studying visual development, especially at the larval stage. For many vertebrates, post-natal visual experience is essential to fine-tune visual devel...
-
Article
Open AccessDifferent Fgfs have distinct roles in regulating neurogenesis after spinal cord injury in zebrafish
Despite conserved developmental processes and organization of the vertebrate central nervous system, only some vertebrates including zebrafish can efficiently regenerate neural damage including after spinal co...
-
Chapter
The Regenerative Potential of the Vertebrate Retina: Lessons from the Zebrafish
The regenerative potential, forward/reverse genetic capabilities and technical advantages of the zebrafish make it an ideal model for studying signals and mechanisms that drive retinal regeneration. Here, we d...
-
Article
Open AccessPtf1a is expressed transiently in all types of amacrine cells in the embryonic zebrafish retina
The vertebrate retina is composed of five major types of neurons: three excitatory (photoreceptors, bipolar cells and ganglion cells) and two inhibitory (horizontal and amacrine cells). The transcription facto...
-
Article
Open AccessVsx2 in the zebrafish retina: restricted lineages through derepression
The neurons in the vertebrate retina arise from multipotent retinal progenitor cells (RPCs). It is not clear, however, which progenitors are multipotent or why they are multipotent.