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Article
Open AccessSpatialPrompt: spatially aware scalable and accurate tool for spot deconvolution and domain identification in spatial transcriptomics
Efficiently map** of cell types in situ remains a major challenge in spatial transcriptomics. Most spot deconvolution tools ignore spatial coordinate information and perform extremely slow on large datasets....
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Article
Sorption of water and ethanol pure vapours and vapour mixtures by four hardwoods
Water is a universal solvent and swelling agent that is widely used in wood industry in association with organic solvents and salts, whether for the fractionation of biomass and the production of bio-based syn...
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Article
Single-cell transcriptome analysis identifies novel biomarkers involved in major liver cancer subtypes
Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the two aggressive subtypes of liver cancer (LC). Immense cellular heterogeneity and cross-talk between cancer and healthy cells mak...
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Article
Association of Klotho with Neuropsychiatric Disorder: A Meta-Analysis
Neuropsychiatric disorders are mainly concerned with the behavioural, emotional and cognition symptoms that may be due to disturbed cerebral functions or extracerebral disease. Klotho protein is an antiaging p...
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Chapter
Emerging Role of Gut Microbiome in Cancer Immunotherapy
Current scientific advances have considerably added to our understanding of the complex association between the microbiome and cancer. Host and microbiota have co-evolved into a “super-organism,” and several p...
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Article
Rhizosphere Priestia species altered cowpea root transcriptome and enhanced growth under drought and nutrient deficiency
Priestia species isolated from the cowpea rhizosphere altered the transcriptome of cowpea roots by colonization and enhanced nutrient uptake, antioxidant mechanisms, and photosynthesis, protecting cowpea from dro...
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Article
The seesaw of diet restriction and lifespan: lessons from Drosophila studies
Diet restriction (DR) studies undergo the implementation of reduced single or multiple component/s of the fly food without causing malnutrition. The question of how and why DR modifies the fate of lifespan in ...
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Article
An overview of two decades of diet restriction studies using Drosophila
Dietary restriction (DR) is a potent forerunner in aging studies capable of influencing lifespan and improving health in various model organisms even in their old age. Despite the importance of protein and car...
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Article
Open AccessGenome-wide interaction and pathway-based identification of key regulators in multiple myeloma
Inherited genetic susceptibility to multiple myeloma has been investigated in a number of studies. Although 23 individual risk loci have been identified, much of the genetic heritability remains unknown. Here ...
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Article
Open AccessInteraction of light regimes and circadian clocks modulate timing of pre-adult developmental events in Drosophila
Circadian clocks have been postulated to regulate development time in several species of insects including fruit flies Drosophila melanogaster. Previously we have reported that selection for faster pre-adult deve...
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Article
Circadian clocks of faster develo** fruit fly populations also age faster
Age-related changes in circadian rhythms have been studied in several model organisms including fruit flies Drosophila melanogaster. Although a general trend of period (τ) lengthening, reduction in rhythm strengt...
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Article
Correlated changes in circadian clocks in response to selection for faster pre-adult development in fruit flies Drosophila melanogaster
Although, circadian clocks are believed to be involved in the regulation of life-history traits such as pre-adult development time and lifespan in fruit flies Drosophila melanogaster, there is very little unequiv...