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Article
Open AccessImmune-mediated hematological disease in dogs is associated with alterations of the fecal microbiota: a pilot study
The dog is the most popular companion animal and is a valuable large animal model for several human diseases. Canine immune-mediated hematological diseases, including immune-mediated hemolytic anemia (IMHA) an...
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Article
Open AccessOrbital stability analysis and photometric characterization of the second Earth Trojan asteroid 2020 XL5
Trojan asteroids are small bodies orbiting around the L4 or L5 Lagrangian points of a Sun-planet system. Due to their peculiar orbits, they provide key constraints to the Solar System evolution models. Despite nu...
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Chapter and Conference Paper
Mechanical Properties and Seismic Performance Research on Primary-Secondary Structure for High-Rise Building
Primary-secondary structures have advantages on constructing high-rise buildings because of its superior structural performance and building adaptability, but systematic research on its mechanical properties a...
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Article
Open AccessMicroring resonator-assisted Fourier transform spectrometer with enhanced resolution and large bandwidth in single chip solution
Single chip integrated spectrometers are critical to bring chemical and biological sensing, spectroscopy, and spectral imaging into robust, compact and cost-effective devices. Existing on-chip spectrometer app...
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Article
Modulation of digital flexor tendon healing by vascular endothelial growth factor gene transfection in a chicken model
A major challenge in tendon injury is the weak intrinsic healing capacity of tendon that may cause rupture of the repair after surgery. Growth factors are believed to be critical during tendon healing. This st...
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Article
Dietary influence on calcitropic hormones and adiposity in Caucasian and African American postmenopausal women assessed by structural equation modeling (SEM)
To examine differences in hydroxycholecalciferol (25(OH)D) and parathyroid hormone (PTH) concentrations between Caucasian and African American (AA) postmenopausal women, as well as the effects of dietary calci...
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Article
Adeno-associated virus-2-mediated TGF-β1 microRNA transfection inhibits adhesion formation after digital flexor tendon injury
Adhesion formation after digital flexor tendon injury greatly affects gliding function of the tendon, which is a major clinical complication after hand surgery. Transforming growth factor beta 1 (TGF-β1) has a...
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Article
Histone deacetylase 5 blocks neuroblastoma cell differentiation by interacting with N-Myc
The N-Myc oncoprotein induces neuroblastoma, which arises from undifferentiated neuroblasts in the sympathetic nervous system, by modulating gene and protein expression and consequently causing cell differenti...
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Article
Photochemical behavior of fenpropathrin and λ-cyhalothrin in solution
The photodegradation processes of fenpropathrin and λ-cyhalothrin were studied in hexane, methanol/water (1:1, v/v), and acetone in both ultraviolet light and simulated sunlight. Intermediates in the photodegrada...
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Article
The effect of liquids on radial segregation of granular mixtures in rotating drums
The presence of liquids can significantly affect the dynamics of granular flow. This paper investigates the effect of liquids on radial segregation of granular mixture in a rotating drum using the discrete ele...
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Article
The histone deacetylase SIRT2 stabilizes Myc oncoproteins
Myc oncoproteins are commonly upregulated in human cancers of different organ origins, stabilized by Aurora A, degraded through ubiquitin–proteasome pathway-mediated proteolysis, and exert oncogenic effects by...
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Article
Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects
Myc oncoproteins and histone deacetylases (HDACs) modulate gene transcription and enhance cancer cell proliferation, and HDAC inhibitors are among the most promising new classes of anticancer drugs. Here, we s...
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Article
Correlation of transmenopausal bone mass in healthy white women: a long-term longitudinal study
It is well established that menopause is associated with accelerated bone loss. However, no study has tested whether bone mass after the menopause transition is correlated with the premenopausal bone mass; tha...
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Article
Association of Estrogen Receptor α and Vitamin D Receptor Gene Polymorphisms with Bone Mineral Density in Chinese Males
Osteoporosis is a common health problem not only in females but also in males, however, studies of osteoporosis in males are relatively rare compared to those in females. This is especially true in genetics st...
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Chapter
Southwest Oncology Group Experience with Intraperitoneal Chemotherapy of Ovarian Cancer
Ovarian cancer (OC) is the leading cause of gynecologic cancer death in the United States, and over 14,000 women will die of this disease in 1999 (1). During the past two decades, median survival has improved dra...
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Article
Phase II trial of biochemotherapy with interferon α, dacarbazine, cisplatin and tamoxifen in metastatic melanoma: a Southwest Oncology Group trial
The therapeutic benefit of adding interferon α (IFNα) to established single-agent and combination chemotherapy regimens for the treatment of metastatic melanoma has not been proven. We designed the present st...
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Article
Applying the topological relationships of form features to retrieve part files from a CAD system
The efficient retrieval of stored CAD files is an area that has received significant attention in recent years. Several Product Data Management products have been developed, most of which are based on the use ...
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Article
Evaluation of merbarone (NSC 336628) in disseminated malignant melanoma
Merbarone, NSC 336628, is an investigational anticancer drug with activity against experimental animal tumors including melanoma. This paper presents results of a Phase II clinical study of merbarone in patien...
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Article
A phase II trial of piroxantrone in disseminated malignant melanoma
Piroxantrone is one of the anthrapyrazoles developed in an effort to combine the broad antitumor activity of the anthracyclines with decreased myocardial toxicity. It has shown activity in metastatic melanoma ...
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Chapter and Conference Paper
Both Wet and Moist Wound Environments Accelerate Cutaneous Healing
Since the early reports on skin wound treatment, showing that skin wounds epithelialize more rapidly under moist conditions than under dry [1, 2], a variety of water and gas permeable dressings have been devel...