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Article
Oncogenic potential of retroviral transactivating genes
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Chapter and Conference Paper
Enhancing Effect of Murine Leukemia Virus on Fibroblast Transformation by Normal BALB/C Mouse DNA Fragments
Several rapidly transforming RNA tumor viruses contain inserts of cellular genetic material. These inserts seem to constitute the so-called onc genes of these viruses (Stephenson et al. 1979). The question arises...
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Chapter
RNA Tumour Viruses: Interesting Interactions with the Host Genome
Horizontally transmitted RNA tumour viruses establish after infection a somatic DNA provirus into cellular DNA. Transcription of the provirus which is under host control usually leads to the synthesis of a 35S...
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Chapter and Conference Paper
Cocultivation as a Tool for the Detection of Oncoviruses in Childhood Leukemia
In our study on the possible role of type-C oncoviruses in human leukemia we applied the technique of cocultivation of human bone marrow cells with an animal indicator cell line. The cocultivation technique pr...
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Chapter
Natural Immunity to Murine Mammary Tumor Viruses
The best-known route of transmission of the mouse mammary tumor virus (MTV) is via the milk (Bittner, 1936). In inbred mouse strains selected for a high incidence of mammary carcinoma, a milkborne tumor-inciti...
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Article
Isolation of infectious C-type oncornavirus from human leukaemic bone marrow cells
C-TYPE ONCORNAVIRUSES are associated with neoplasms of the haemopoietic organs in several vertebrate species1. Molecular hybridisation studies have revealed the presence of an RNA species in human leukaemias that...
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Article
C-type virus antigens detected by immuno-fluorescence in human bone tumour cultures
IN several animal species, C-type oncogenic RNA viruses (oncornaviruses) cause malignant tumours of mesodermal origin, such as leukaemia, lymphomas and different kinds of sarcoma1. C-type oncornaviruses have rare...
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Article
Leukaemogenic effect of repeated inoculations with small doses of Tennant virus in BALB/c mice
DOSE-RESPONSE studies of oncogenic viruses in animals are usually restricted to single inoculations. The study of the effect of dose fractionation has been a rather neglected subject in this field. An importan...
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Article
Breast Cancer
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Article
Book reviews
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Article
Book reviews
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Article
Book reviews
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Article
Evidence for overdominance inDrosophila melanogaster
In artificial populations ofDrosophila melanogaster the mutantsvermilion (v) andcinnabar (cn), both interfering with eye pigment formation, appeared to be balanced against wild type, indicating that the heterozyg...
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Article
Book reviews
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Article
Some interrelations between density and genetic structure of aDrosophila population
The importance of relative growth rates and their variances in larval populations is discussed.