16 Result(s)
within
P Ghadirian
English
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Article
Open AccessIncidence of colorectal cancer in BRCA1 and BRCA2 mutation carriers: results from a follow-up study
The BRCA1 and BRCA2 genes confer increased susceptibility to breast and ovarian cancer and to a spectrum of other cancers. There is controversy regarding the risk of colorectal cancer conferred by germline mutati...
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Open AccessThe incidence of pancreatic cancer in BRCA1 and BRCA2 mutation carriers
Germline mutations in BRCA1 and BRCA2 predispose to pancreatic cancer. We estimated the incidence of pancreatic cancer in a cohort of female carriers of BRCA1 and BRCA2 mutation. We also estimated survival rates ...
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Article
Open AccessPredictors of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers
The objective of this study was to estimate the risk of contralateral breast cancer in BRCA1 and BRCA2 carriers; and measure the extent to which host, family history, and cancer treatment-related factors modif...
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Open AccessRapid progression of prostate cancer in men with a BRCA2 mutation
Men with BRCA2 mutations have been found to be at increased risk of develo** prostate cancer. There is a recent report that BRCA2 carriers with prostate cancer have poorer survival than noncarrier prostate canc...
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Germline BRCA2 mutations and the risk of esophageal squamous cell carcinoma
The incidence of esophageal squamous cell carcinoma (ESCC) is very high among the Turkmen population of Iran. Family studies suggest a genetic component to the disease. Turkmen are ethnically homogenous and ar...
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Article
Diet quality and BRCA-associated breast cancer risk
Although it has been suggested that dietary energy intake restriction may be related to reduced BRCA-associated breast cancer (BC) risk, it is currently not known whether overall diet quality could predict the BC...
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Article
Variation of selenium concentration in toenails following long-term storage, washing and reactor irradiation
Neutron activation analysis of toenails is often used to monitor body selenium in studies looking for an association between selenium deficiency and an increased cancer risk. In this study, 87 toenail samples ...
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Diet, lifestyle and BRCA-related breast cancer risk among French-Canadians
Although the connection between diet, lifestyle and hormones suggests that nutritional and lifestyle factors may exert an influence in the etiology of breast cancer (BC), it is not clear whether these factors ...
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Article
Open AccessSpecific fatty acid intake and the risk of pancreatic cancer in Canada
The possible association of specific fatty acid (FA) intake and pancreatic cancer risk was investigated in a population-based case–control study of 462 histologically confirmed cases and 4721 frequency-matched...
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Article
Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma
A prospective study of 149 unselected incident cases of pancreatic adenocarcinoma and 146 ethnically-matched controls found no associations between GSTM1 (adjusted odds ratio (AOR) 1.14), GSTT1 (AOR: 1.19) and CY...
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Article
Open AccessNo association between P53 codon 72 polymorphism and risk of squamous cell carcinoma of the head and neck
An initial report suggested that patients homozygous for the arginine allele at codon 72 of P53 were at increased risk for human papillomavirus (HPV)-related cervical cancer, but other groups have not confirmed t...
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Nutritional factors and prostate cancer: a case-control study of French Canadians in Montreal, Canada
The relationship between the risk of prostate cancer and dietary intake of energy, fat, vitamin A, and other nutrients was investigated in a case-control study conducted in Montreal (Quebec), Canada. French Ca...
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Investigational strategies for detection and intervention in early-stage pancreatic cancer
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Reported family aggregation of pancreatic cancer within a population-based case-control study in the francophone community in Montreal, Canada
As part of the SEARCH Collaborating Study Group of the International Agency for Research on Cancer (IARC), a population-based case-control study of cancer of the pancreas was conducted in Montreal, interviewin...
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Alcohol, Tobacco and Oesophageal Cancer: An International Comparison
Numerous case-control studies have been carried out in different parts of the world regarding the role of alcohol in the development of oesophageal cancer. Since at least in the West, heavy drinkers are freque...
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Article
Oesophageal Cancer Studies in the Caspian Littoral of Iran: The Caspian Cancer Registry
The results of the first 3 years of cancer registration on the Caspian Littoral are described. The main finding, confirming previous reports, is a very large variation within the region of the incidence of oes...
