15 Result(s)
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Daniel S. Longnecker
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Article
Erratum to: Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study
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Article
Autoimmune pancreatitis: the clinicopathological characteristics of the subtype with granulocytic epithelial lesions
Autoimmune pancreatitis (AIP) has been established as a distinct form of chronic pancreatitis that is distinguishable from other types such as alcoholic, hereditary or obstructive chronic pancreatitis. AIP see...
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Article
Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study
Now that more than two decades have passed since the first reports of intraductal papillary-mucinous neoplasms (IPMNs), it has become clear that IPMN consists of a spectrum of neoplasms with both morphological...
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Article
Growing colorectal tumors: minimizing microbial and stromal competition and assessing in vitro selection pressures
Development of primary colorectal cancer cell lines ishampered by contamination from regional microbes, overgrowthof stromal cells, and purported genetic drift from selectionpressures in vitro. We initiated 32 pr...
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Article
Simultaneous mucinous cystadenoma of ovary and mucinous cystadenocarcinoma of pancreas
Mucinous cystic tumors were discovered synchronously in the tail of the pancreas and in the right ovary of an adult female. Both tumors were amenable to surgical resection. The pancreatic tumor was a noninvasi...
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Article
Clinical pathology of pancreatic disorders, J. A. Lott, ed.
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Chapter
Clues from Experimental Models
Selecting or creating an animal model of carcinoma of the pancreas is a complex process. One must ask what is being modeled. The reflex response is “ductal adenocarcinoma,” because this is the most common hist...
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Article
Do oncogene and tumor suppressor gene abnormalities vary with type of carcinoma of the pancreas?
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Article
Investigational strategies for detection and intervention in early-stage pancreatic cancer
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Chapter
Protease Inhibitors and Pancreatic Carcinogenesis
In the United States, pancreatic cancer is the fifth most common cause of death due to cancer, claiming over 25,000 lives annually (Silverberg and Lubera, 1989). Males are at a slightly higher risk than female...
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Article
Hormones and pancreatic cancer
Several polypeptide hormones have been demonstrated to stimulate or inhibit cell division in the cells of the pancreas. Therefore, receptors for these hormones have been sought in pancreatic carcinomas, and se...
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Effects of sex steroid hormones on pancreatic cancer in the rat
The incidence of spontaneous and induced neoplasms of the exocrine pancreas in rats is higher in males than in females. Castration, ovariectomy, and hormone replacement with estradiol and testosterone have bee...
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Chapter
Role of Dietary Fat in Experimental Pancreatic Carcinogenesis
Pancreatic cancer ranks eighth with respect to incidence of cancer in the United States. However, it is the fifth most common cause of death due to cancer with about 25,000 deaths per year (1). Diagnosis of pa...
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Chapter
Carcinogenesis in gastrointestinal organs
Concepts of carcinogenesis are evolving rapidly and have been refined into a multistep or multistage scheme during the past few decades. Longer reviews of progress in experimental carcinogenesis summarize the ...
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Chapter
Early Morphologic Markers of Carcinogenicity in Rat Pancreas
Carcinomas have been experimentally induced in the pancreas of rats by several chemicals since Hayashi and Hasegawa first reported induction of hyperplastic nodules and acinar cell adenomas in pancreas of rats...
