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Article
Systemic treatment in advanced phyllodes tumor of the breast: a multi-institutional European retrospective case-series analyses
We aimed at investigating outcome of systemic treatments in advanced breast PT.
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Article
Cervical Lymph Node Metastases of Papillary Thyroid Carcinoma, in the Central and Lateral Compartments, in Children and Adolescents: Predictive Factors
The aim of our study was to identify predictive factors for lymph node metastases (LNM) in children and adolescents with papillary thyroid carcinoma (PTC) and their impact on survival.
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Article
Surgical management of papillary thyroid carcinoma in childhood and adolescence: an Italian multicenter study on 250 patients
The extent of surgery for pediatric papillary thyroid carcinoma is debatable. The aim of this study was to evaluate the feasibility of offering pediatric patients a tailored surgical approach based on certain ...
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Article
Open AccessThe Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx)
The Polycomb group (PcG) proteins regulate stem cell differentiation via the repression of gene transcription, and their deregulation has been widely implicated in cancer development. The PcG protein Enhancer ...
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Article
Functional inactivation of the WTX gene is not a frequent event in Wilms’ tumors
For many years the precise genetic etiology of the majority of Wilms’ tumors has remained unexplained. Recently, the WTX gene, mapped to chromosome Xq11.1, has been reported to be lost or mutated in approximately...
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Article
Intramedullary astrocytoma with granular cell differentiation
Granular cell astrocytomas are uncommon tumors of the central nervous system (CNS) of which no cases have been documented in the spinal cord. This variant of glioma should not be confused with benign granular ...
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Article
Open AccessStage 4 neuroblastoma: sequential hemi-body irradiation or high-dose chemotherapy plus autologous haemopoietic stem cell transplantation to consolidate primary treatment
The aim of the present study was to evaluate the effectiveness of two consecutive nonrandomised treatment programs applied between 1989 and 1999 at the Istituto Nazionale Tumori of Milan in an unselected cohor...
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Article
Differentiation in paediatric peripheral primitive neuroectodermal tumours of bone
Differentiation was studied in 73 paediatric peripheral primitive neurorectodermal tumours (pPNETs) of bone observed during 1974 through 1992. The presence of rosettes, pseudorosettes, and/or a rosette-like a...
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Article
Changes in glial fibrillary acidic protein and karyotype during culturing of two cell lines established from human glioblastoma multiforme
Two human cell lines (GL15 and GL22) derived from glioblastoma multiforme were established and characterized by immunohistochemical and cytogenetic techniques. The expression of glial fibrillary acidic protein...