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  1. Article

    Open Access

    Neurobehavioral, neurotransmitter and redox modifications in Nauphoeta cinerea under mixed heavy metal (silver and mercury) exposure

    Heavy metals are encountered in nature, and are used in several human endeavors, including in dental fillings. It is well known that the safety of metals depends on their chemical form, as well as the dose and...

    Olawande C. Olagoke, Opeyemi B. Ogunsuyi, Famutimi E. Mayokun… in BMC Research Notes (2024)

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  2. No Access

    Article

    Effect of curcumin on gene expression of selected inflammatory markers in cortex and hippocampus of pilocarpine-induced seizure in rats on a routine exercise program

    Neuroinflammation is critical to the pathogenesis and progression of epileptic seizures, and the inflammatory pathway is controlled by an interplay of highly regulated mediators such as cytokines. The combinat...

    Opeyemi B. Ogunsuyi in Comparative Clinical Pathology (2024)

  3. Article

    Open Access

    Bitter gourd flavored Non-Alcoholic Wheat Beer (NAWB) exhibited antidiabetic properties by modulating carbohydrate metabolizing enzymes and upregulates insulin and GLUT-2 mRNA expressions in High Fat Diet/Streptozotocin (HFD/STZ) induced diabetic rats

    To improve the control of Type 2 diabetes (T2D), this study investigated the potential benefits of an alcohol-free beer flavored with bitter gourd leaves, a plant with proven hypoglycemic properties. The high ...

    Gbenga P. Akerele, Bukola C. Adedayo… in Food Production, Processing and Nutrition (2023)

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  4. No Access

    Article

    Effect of Bitter-leaf (Vernonia amygdalina) Flavored Non-alcoholic Wheat Beer (NAWB) on, Insulin and GLUT-2 expression in Pancreas of High fat diet/Streptozotocin (HFD/STZ) Induced Diabetic Wistar Rats

    In the management of type 2 diabetes (T2D), dietary intervention has been proposed to be highly effective. This study, therefore, investigated the effect of bitter leaf-flavored non-alcoholic wheat beer (NAWB)...

    Gbenga P. Akerele, Bukola C. Adedayo… in Journal of Diabetes & Metabolic Disorders (2023)

  5. No Access

    Article

    Effect of Solanum vegetables on memory index, redox status, and expressions of critical neural genes in Drosophila melanogaster model of memory impairment

    African eggplant (Solanum macrocarpon L) (AE) and Black Nightshade (Solanum nigrum L) (BN) leaves are green leafy vegetables with nutritional and ethnobotanical values. We have previously characterized the vegeta...

    Opeyemi B. Ogunsuyi, Olawande C. Olagoke, Blessing A. Afolabi… in Metabolic Brain Disease (2022)

  6. No Access

    Article

    Purple onion in combination with garlic exerts better ameliorative effects on selected biomarkers in high-sucrose diet-fed fruit fly (Drosophila melanogaster)

    Garlic and purple onion are two vegetables widely used globally for culinary purposes. These vegetables have been previously reported to exhibit several medicinal properties including antidiabetic, antihyperte...

    Stephen Adeniyi Adefegha, Opeyemi B. Ogunsuyi… in Comparative Clinical Pathology (2020)

  7. No Access

    Article

    Gallic acid protects against neurochemical alterations in transgenic Drosophila model of Alzheimer’s disease

    This study evaluated the effect of gallic acid on some selected biomarkers in Drosophila melanogaster model of Alzheimer’s disease (AD). Transgenic D. melanogaster expressing human amyloid precursor protein and β...

    Opeyemi B. Ogunsuyi, Ganiyu Oboh, Odunayo O. Oluokun… in Advances in Traditional Medicine (2020)

  8. No Access

    Article

    Effect of combinations of caffeine and caffeic acid on key enzymes linked to hypertension (in vitro)

    Caffeine (CA) and caffeic acid (CAF) are two bioactive phytochemicals found richly distributed in many plant foods such as coffee in different proportions. CA, an alkaloid, is adjudged world’s most consumed fo...

    Ganiyu Oboh, Opeyemi O. Adeoyo… in Oriental Pharmacy and Experimental Medicine (2018)

  9. No Access

    Article

    Jimson weed (Datura stramonium L.) alkaloid extracts modulate cholinesterase and monoamine oxidase activities in vitro: possible modulatory effect on neuronal function

    Despite the well-established medicinal values of Jimson weed (Datura stramonium L.), this medicinal plant has been associated with neurological effects such as hallucination and anxiety in folklore. This study ex...

    Adedayo O. Ademiluyi, Opeyemi B. Ogunsuyi, Ganiyu Oboh… in Comparative Clinical Pathology (2016)

  10. No Access

    Article

    A comparative study on antihypertensive and antioxidant properties of phenolic extracts from fruit and leaf of some guava (Psidium guajava L.) varieties

    Investigation of antihypertensive and antioxidant properties of fruit and leaf extracts from four varieties (giant white, small white, stripped and pink) of guava (Psidium guajava L.) in vitro was the focus of th...

    Adedayo O. Ademiluyi, Ganiyu Oboh, Opeyemi B. Ogunsuyi… in Comparative Clinical Pathology (2016)

  11. No Access

    Chapter

    Quercetin and Its Role in Chronic Diseases

    Quercetin, a member of the flavonoid class of polyphenol, is one of the most abundantly distributed flavonoids found in various food sources such as fruits, vegetables, nuts, wine and seeds. Quercetin and quer...

    Ganiyu Oboh, Ayokunle O. Ademosun, Opeyemi B. Ogunsuyi in Drug Discovery from Mother Nature (2016)