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  1. No Access

    Article

    Ferumoxytol Can Be Used for Quantitative Magnetic Particle Imaging of Transplanted Stem Cells

    To evaluate, if clinically translatable ferumoxytol nanoparticles can be used for in vivo detection and quantification of stem cell transplants with magnetic particle imaging (MPI).

    Hossein Nejadnik, Prachi Pandit, Olga Lenkov… in Molecular Imaging and Biology (2019)

  2. Article

    Open Access

    Nanoparticle enhanced MRI can monitor macrophage response to CD47 mAb immunotherapy in osteosarcoma

    CD47 monoclonal antibodies (mAbs) activate tumor-associated macrophages (TAMs) in sarcomas to phagocytose and eliminate cancer cells. Though CD47 mAbs have entered clinical trials, diagnostic tests for monitor...

    Suchismita Mohanty, Ketan Yerneni, Johanna Lena Theruvath… in Cell Death & Disease (2019)

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  3. No Access

    Article

    Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

    Until now, the Food and Drug Administration (FDA)-approved iron supplement ferumoxytol and other iron oxide nanoparticles have been used for treating iron deficiency, as contrast agents for magnetic resonance ...

    Saeid Zanganeh, Gregor Hutter, Ryan Spitler, Olga Lenkov… in Nature Nanotechnology (2016)

  4. Article

    Open Access

    Macrophage phagocytosis alters the MRI signal of ferumoxytol-labeled mesenchymal stromal cells in cartilage defects

    Human mesenchymal stem cells (hMSCs) are a promising tool for cartilage regeneration in arthritic joints. hMSC labeling with iron oxide nanoparticles enables non-invasive in vivo monitoring of transplanted cells ...

    Hossein Nejadnik, Olga Lenkov, Florian Gassert, Deborah Fretwell… in Scientific Reports (2016)

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