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  1. No Access

    Article

    Challenges of pediatric pharmacotherapy: A narrative review of pharmacokinetics, pharmacodynamics, and pharmacogenetics

    Personalized pharmacotherapy, including for the pediatric population, provides optimal treatment and has emerged as a major trend owing to advanced drug therapeutics and diversified drug selection. However, it...

    Hirofumi Watanabe, Nobuhiko Nagano… in European Journal of Clinical Pharmacology (2024)

  2. No Access

    Article

    Normal reference values for left atrial strains and strain rates in school children assessed using two-dimensional speckle-tracking echocardiography

    Left atrium (LA) function is a known predictive marker of heart failure in adults. Few reports of LA function analyses using LA strain (ɛ) and strain rate (SR) measurements in children exist. Thus, this study aim...

    Shino Jimbo, Nobutaka Noto, Hirotsugu Okuma, Masataka Kato… in Heart and Vessels (2020)

  3. Article

    Open Access

    Reassessment of carotid intima-media thickness by standard deviation score in children and adolescents after Kawasaki disease

    Previous studies that used carotid ultrasound have been largely conflicting in regards to whether or not patients after Kawasaki disease (KD) have a greater carotid intima-media thickness (CIMT) than controls....

    Nobutaka Noto, Masataka Kato, Yuriko Abe, Hiroshi Kamiyama… in SpringerPlus (2015)

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  4. No Access

    Article

    Age-Related Acceleration of Endothelial Dysfunction and Subclinical Atherosclerosis in Subjects with Coronary Artery Lesions After Kawasaki Disease

    The objective of this study was to test the hypothesis that accelerated endothelial dysfunction and the development of premature atherosclerosis are associated with age in subjects with coronary artery lesions...

    Nobutaka Noto, Tomoo Okada, Kensuke Karasawa, Mamoru Ayusawa… in Pediatric Cardiology (2009)

  5. Article

    Useful Method of Low-dose Dobutamine Quantitative Gated SPECT in Kawasaki Disease with Severe Coronary Arterial Lesion

    Quantitative gated SPECT (QGS)is useful imaging for the myocardial perfusion and left ventricular function. To assess simultaneously myocardial perfusion and left ventricular contractile reserve by Low-dose Do...

    Kensuke Karasawa, Kazuo Taniguti, Mamoru Ayusawa, Nobutaka Noto… in Pediatric Research (2003)

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  6. Article

    Estimation of “Selective” Intravenous Gamma Globulin Treatment Indicated by Harada Score

    Harada score, which was originally constructed as a guideline for indication of intravenous gamma globulin (IVGG) in research group of Kawasaki disease promoted by the Ministry of Health (Kouseishou), had been...

    Mamoru Ayusawa, Hiroshi Kanamaru, Kensuke Karasawa, Nobutaka Noto… in Pediatric Research (2003)

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