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  1. No Access

    Article

    Skeletal and upper airway stability following modified maxillomandibular advancement for treatment of obstructive sleep apnea in skeletal class I or II deformity

    Maxillomandibular advancement (MMA) is an effective short-term treatment for obstructive sleep apnea (OSA). This study aimed to evaluate the long-term stability of the facial skeleton, upper airway, and its su...

    Sitawan Navasumrit, Ying-An Chen, Yuh-Jia Hsieh in Clinical Oral Investigations (2022)

  2. Article

    Open Access

    Monocytic C-C chemokine receptor 5 expression increases in in vitro intermittent hypoxia condition and in severe obstructive sleep apnea patients

    Obstructive sleep apnea (OSA) patients have higher risk of cardiovascular disease. C-C chemokine receptor 5 (CCR5), as an important receptor for monocyte recruitment and the initiation of atherosclerosis, was ...

    Li-Pang Chuang, Ning-Hung Chen, Shih-Wei Lin, Han-Chung Hu in Sleep and Breathing (2019)

  3. No Access

    Article

    Correlation between structural progression in glaucoma and obstructive sleep apnea

    To investigate the correlation between obstructive sleep apnea (OSA) severity and the structural and functional progression in patients with glaucoma.

    Yuan-Yao Fan, Wei-Wen Su, Chun-Hsiu Liu, Henry Shen-Lih Chen, Shiu-Chen Wu in Eye (2019)

  4. No Access

    Article

    Home sleep apnea testing: comparison of manual and automated scoring across international sleep centers

    To determine the agreement between the manual scoring of home sleep apnea tests (HSATs) by international sleep technologists and automated scoring systems.

    Ulysses J. Magalang, Jennica N. Johns, Katherine A. Wood in Sleep and Breathing (2019)

  5. No Access

    Article

    Reply to “Obstructive sleep apnea patients without hypertension or diabetes and subsequent incidence of chronic kidney disease” by Kawada (letter to the editor)

    Yu-Sheng Lin, Pi-Hua Liu, Ning-Hung Chen in Sleep and Breathing (2018)

  6. Article

    Open Access

    Airway Changes after Cleft Orthognathic Surgery Evaluated by Three-Dimensional Computed Tomography and Overnight Polysomnographic Study

    Cleft lip and palate is the most common congenital craniofacial anomaly. Up to 60% of these patients will benefit from cleft orthognathic surgery, which consists primarily of maxillary advancement and mandibul...

    Chun-Shin Chang, Christopher Glenn Wallace, Yen-Chang Hsiao in Scientific Reports (2017)

  7. Article

    Open Access

    The gender difference of snore distribution and increased tendency to snore in women with menopausal syndrome: a general population study

    Sleep-disordered breathing (SDB) is a prevalent disorder with a major impact in women, especially postmenopausal women. However, few studies have investigated the prevalence of a specific SDB, snoring, among w...

    Li-Pang Chuang, Shih-Wei Lin, Li-Ang Lee, Hsueh-Yu Li in Sleep and Breathing (2017)

  8. Article

    Open Access

    Simple obstructive sleep apnea patients without hypertension or diabetes accelerate kidney dysfunction: a population follow-up cohort study from Taiwan

    Obstructive sleep apnea (OSA) is common in patients on hemodialysis, but its correlation with chronic kidney disease (CKD) is not clear. We aimed to clarify the relationship between OSA without hypertension or...

    Yu-Sheng Lin, Pi-Hua Liu, Shi-Wei Lin, Li-Pang Chuang, Wan-**g Ho in Sleep and Breathing (2017)

  9. Article

    Open Access

    Invasive fungal tracheobronchitis in mechanically ventilated critically ill patients: underlying conditions, diagnosis, and outcomes

    Invasive fungal tracheobronchitis (IFT) is a severe form of pulmonary fungal infection that is not limited to immunocompromised patients. Although respiratory failure is a crucial predictor of death, informati...

    Chun-Yu Lin, Wei-Lun Liu, Che-Chia Chang, Hou-Tai Chang in Annals of Intensive Care (2017)

  10. Article

    Open Access

    Factors responsible for poor sleep quality in patients with chronic obstructive pulmonary disease

    Sleep disturbance is a common complaint in patients with chronic obstructive lung disease (COPD). However, the factors resulting in sleep disturbance remain unclear. This retrospective, observational, multicen...

    Chih-Hao Chang, Li-Pang Chuang, Shih-Wei Lin, Chung-Shu Lee in BMC Pulmonary Medicine (2016)

  11. Article

    Open Access

    Snoring Sounds Predict Obstruction Sites and Surgical Response in Patients with Obstructive Sleep Apnea Hypopnea Syndrome

    Snoring sounds generated by different vibrators of the upper airway may be useful indicators of obstruction sites in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). This study aimed to investi...

    Li-Ang Lee, Yu-Lun Lo, Jen-Fang Yu, Gui-She Lee, Yung-Lun Ni in Scientific Reports (2016)

  12. Article

    Open Access

    The Frequency and Energy of Snoring Sounds Are Associated with Common Carotid Artery Intima-Media Thickness in Obstructive Sleep Apnea Patients

    Obstructive sleep apnea (OSA) is a known risk factor for atherosclerosis. We investigated the association of common carotid artery intima-media thickness (CCA-IMT) with snoring sounds in OSA patients. A total ...

    Guo-She Lee, Li-Ang Lee, Chao-Yung Wang, Ning-Hung Chen in Scientific Reports (2016)

  13. No Access

    Article

    Increased MCP-1 gene expression in monocytes of severe OSA patients and under intermittent hypoxia

    Obstructive sleep apnea (OSA) is known to be a risk factor of coronary artery disease. Monocyte chemoattractant protein-1 (MCP-1), as a critical factor for monocyte infiltration, is known to play a role in the...

    Li-Pang Chuang, Ning-Hung Chen, Yuling Lin, Wen-Shan Ko in Sleep and Breathing (2016)

  14. Article

    Open Access

    Sleep medicine in Taiwan

    The sleep medicine is a young medical science in Taiwan. It began from less than 10 sleep beds 20 years ago in four hospitals all over Taiwan. By the organization of sleep team in Chang Gung Memorial Hospital ...

    Ning-Hung Chen, Liang-Wen Hang, Chia-Mo Lin in Sleep and Biological Rhythms (2016)

  15. Article

    Open Access

    Treatment of snoring with positional therapy in patients with positional obstructive sleep apnea syndrome

    Position therapy plays a role in treating snoring and obstructive sleep apnea syndrome (OSAS). The purpose of this study was to investigate whether position therapy using a head-positioning pillow (HPP) could ...

    Wen-Chyuan Chen, Li-Ang Lee, Ning-Hung Chen, Tuan-Jen Fang in Scientific Reports (2015)

  16. Article

    Open Access

    Diffuse alveolar damage associated mortality in selected acute respiratory distress syndrome patients with open lung biopsy

    Diffuse alveolar damage (DAD) is the pathological hallmark of acute respiratory distress syndrome (ARDS), however, the presence of DAD in the clinical criteria of ARDS patients by Berlin definition is little k...

    Kuo-Chin Kao, Han-Chung Hu, Chih-Hao Chang, Chen-Yiu Hung, Li-Chung Chiu in Critical Care (2015)

  17. Article

    Open Access

    Clinical outcomes and molecular ty** of heterogenous vancomycin-intermediate Staphylococcus aureus bacteremia in patients in intensive care units

    Staphylococcus aureus is one of most common pathogens in humans. Methicillin-resistant S. aureus (MRSA) accounts for 64 % of S. aureus bacteremia isolated in intensive care units (ICUs), and heteroresistant vanco...

    Han-Chung Hu, Kuo-Chin Kao, Li-Chung Chiu, Chih-Hao Chang in BMC Infectious Diseases (2015)

  18. Article

    Open Access

    Activation of Src-dependent Smad3 signaling mediates the neutrophilic inflammation and oxidative stress in hyperoxia-augmented ventilator-induced lung injury

    Mechanical ventilation and concomitant administration of hyperoxia in patients with acute respiratory distress syndrome can damage the alveolar epithelial and capillary endothelial barrier by producing inflamm...

    Li-Fu Li, Chung-Shu Lee, Yung-Yang Liu, Chih-Hao Chang in Respiratory Research (2015)

  19. No Access

    Article

    Immediate and Long-term Neurocognitive Outcome in Patients with Obstructive Sleep Apnea Syndrome After Continuous Positive Airway Pressure Treatment

    Neurocognitive dysfunction is a major clinical consequence in patients with obstructive sleep apnea syndrome (OSAS). The effects of continuous positive airway pressure (CPAP) treatment, as the gold standard of...

    Shih-Wei Lin, Yu-Ting Chou, Kuo-Chin Kao in Indian Journal of Otolaryngology and Head … (2015)

  20. Article

    Open Access

    The utility of surgical lung biopsy in cancer patients with acute respiratory distress syndrome

    This retrospective study evaluated the utility and safety of surgical lung biopsy (SLB) in cancer patients with acute respiratory distress syndrome (ARDS).

    Chih-Hao Chang, Kuo-Chin Kao, Han-Chung Hu in Journal of Cardiothoracic Surgery (2013)

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