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  1. Article

    Open Access

    Mechanical power during extracorporeal membrane oxygenation and hospital mortality in patients with acute respiratory distress syndrome

    Mechanical power (MP) refers to the energy delivered by a ventilator to the respiratory system per unit of time. MP referenced to predicted body weight (PBW) or respiratory system compliance have better predic...

    Li-Chung Chiu, Shih-Wei Lin, Li-Pang Chuang, Hsin-Hsien Li, Pi-Hua Liu in Critical Care (2021)

  2. Article

    Open Access

    Impact of corticosteroid treatment on clinical outcomes of influenza-associated ARDS: a nationwide multicenter study

    Corticosteroid treatment has been widely used in the treatment of septic shock, influenza, and ARDS, although some previous studies discourage its use in severe influenza patients. This multicenter retrospecti...

    Ming-Ju Tsai, Kuang-Yao Yang, Ming-Cheng Chan, Kuo-Chin Kao in Annals of Intensive Care (2020)

  3. Article

    Open Access

    Monocytic C-C chemokine receptor 5 expression increases in in vitro intermittent hypoxia condition and in severe obstructive sleep apnea patients

    Obstructive sleep apnea (OSA) patients have higher risk of cardiovascular disease. C-C chemokine receptor 5 (CCR5), as an important receptor for monocyte recruitment and the initiation of atherosclerosis, was ...

    Li-Pang Chuang, Ning-Hung Chen, Shih-Wei Lin, Han-Chung Hu in Sleep and Breathing (2019)

  4. Article

    Open Access

    Predictors of survival in patients with influenza pneumonia-related severe acute respiratory distress syndrome treated with prone positioning

    Patients with influenza complicated with pneumonia are at high risk of rapid progression to acute respiratory distress syndrome (ARDS). Prone positioning with longer duration and lung-protective strategies mig...

    Kuo-Chin Kao, Ko-Wei Chang, Ming-Cheng Chan, Shinn-Jye Liang in Annals of Intensive Care (2018)

  5. Article

    Open Access

    Survival predictors in elderly patients with acute respiratory distress syndrome: a prospective observational cohort study

    Acute respiratory distress syndrome (ARDS) has a high mortality rate in intensive care units (ICU). The elderly patients remain to be increased of ICU patients. The aim is to investigate the survival predictor...

    Kuo-Chin Kao, Meng-Jer Hsieh, Shih-Wei Lin, Li-Pang Chuang in Scientific Reports (2018)

  6. Article

    Open Access

    Predictors of Early Onset Multiple Organ Dysfunction in Major Burn Patients with Ventilator Support: Experience from A Mass Casualty Explosion

    Organ dysfunction is common in patients with major burns and associated with poor outcomes. The risk factors for early onset multiple organ dysfunction syndrome (MODS) in major burn patients with invasive vent...

    Jia-Yih Feng, Jung-Yien Chien, Kuo-Chin Kao, Cheng-Liang Tsai in Scientific Reports (2018)

  7. Article

    Open Access

    Dynamic driving pressure associated mortality in acute respiratory distress syndrome with extracorporeal membrane oxygenation

    The survival predictors and optimal mechanical ventilator settings in patients with severe acute respiratory distress syndrome (ARDS) undergoing extracorporeal membrane oxygenation (ECMO) are uncertain. This s...

    Li-Chung Chiu, Han-Chung Hu, Chen-Yiu Hung, Chih-Hao Chang in Annals of Intensive Care (2017)

  8. Article

    Open Access

    Invasive fungal tracheobronchitis in mechanically ventilated critically ill patients: underlying conditions, diagnosis, and outcomes

    Invasive fungal tracheobronchitis (IFT) is a severe form of pulmonary fungal infection that is not limited to immunocompromised patients. Although respiratory failure is a crucial predictor of death, informati...

    Chun-Yu Lin, Wei-Lun Liu, Che-Chia Chang, Hou-Tai Chang in Annals of Intensive Care (2017)

  9. Article

    Open Access

    Comparison of community-acquired, hospital-acquired, and intensive care unit-acquired acute respiratory distress syndrome: a prospective observational cohort study

    Acute respiratory distress syndrome (ARDS) is a syndrome characterized by diffuse pulmonary edema and severe hypoxemia that usually occurs after an injury such as sepsis, aspiration and pneumonia. Little is kn...

    Kuo-Chin Kao, Han-Chung Hu, Meng-Jer Hsieh, Ying-Huang Tsai in Critical Care (2015)

  10. Article

    Open Access

    Diffuse alveolar damage associated mortality in selected acute respiratory distress syndrome patients with open lung biopsy

    Diffuse alveolar damage (DAD) is the pathological hallmark of acute respiratory distress syndrome (ARDS), however, the presence of DAD in the clinical criteria of ARDS patients by Berlin definition is little k...

    Kuo-Chin Kao, Han-Chung Hu, Chih-Hao Chang, Chen-Yiu Hung, Li-Chung Chiu in Critical Care (2015)

  11. Article

    Open Access

    Clinical outcomes and molecular ty** of heterogenous vancomycin-intermediate Staphylococcus aureus bacteremia in patients in intensive care units

    Staphylococcus aureus is one of most common pathogens in humans. Methicillin-resistant S. aureus (MRSA) accounts for 64 % of S. aureus bacteremia isolated in intensive care units (ICUs), and heteroresistant vanco...

    Han-Chung Hu, Kuo-Chin Kao, Li-Chung Chiu, Chih-Hao Chang in BMC Infectious Diseases (2015)

  12. No Access

    Article

    Immediate and Long-term Neurocognitive Outcome in Patients with Obstructive Sleep Apnea Syndrome After Continuous Positive Airway Pressure Treatment

    Neurocognitive dysfunction is a major clinical consequence in patients with obstructive sleep apnea syndrome (OSAS). The effects of continuous positive airway pressure (CPAP) treatment, as the gold standard of...

    Shih-Wei Lin, Yu-Ting Chou, Kuo-Chin Kao in Indian Journal of Otolaryngology and Head … (2015)

  13. Article

    Open Access

    The utility of surgical lung biopsy in cancer patients with acute respiratory distress syndrome

    This retrospective study evaluated the utility and safety of surgical lung biopsy (SLB) in cancer patients with acute respiratory distress syndrome (ARDS).

    Chih-Hao Chang, Kuo-Chin Kao, Han-Chung Hu in Journal of Cardiothoracic Surgery (2013)

  14. Article

    Open Access

    Invasive fungal infection among hematopoietic stem cell transplantation patients with mechanical ventilation in the intensive care unit

    Invasive fungal infection (IFI) is associated with high morbidity and high mortality in hematopoietic stem cell transplantation (HSCT) patientsThe purpose of this study was to assess the characteristics and ou...

    Chen-Yiu Hung, Kuo-Chin Kao, Po-Nan Wang, Han-Chung Hu in BMC Infectious Diseases (2012)